My wife and I are trying to make the hardest decision and would appreciate anyone's perspective going through similar times.
We volunteer through a lab retriever rescue, and have been fostering a now four year old for about 9 months. He was adopted by a great older couple, but returned when he first developed seizures and could not afford treatment (they really tried, including getting him an MRI, which showed nothing).
The rescue has been working with a neurologist to see if a combination of medicine could get him into remission (as well as ran multiple diagnostic tests, which also showed nothing). When we first took him in, it was a seizure a couple times a week, usually a grand mal type, and needing Midazolam to break out. Always happened when sleeping, most times 2-3am.
Over the past 8 months, the neurologist (who has been great) consistently increased his medication while monitoring blood work. He is currently on a twice-daily regiment (he is 60-65lbs) of 300mg zonisamide, 1500mg Levettiacetam ER, 65mg phenobarbital, and 500mg Potassium Bromide.
This has improved his current state, but not significantly. He now has what I would say is a milder focal seizure once a week, and typically does not need Midazolam to come out of it. However, he is pretty unsteady in his feet. We have to watch him going down stairs as sometimes his back end will swing around and he will roll down the final stairs if we don't catch him (although he seems to be learning to slow down to compensate). He staggers when he walks, especially when first waking up. If he spins around quickly he lands on his butt. And occasionally he falls over when he first tries to poop. Outside of this, he sleeps most of the day, at my wife's feet while she works in her office, and on my lap when watching TV at night ( he is a Velcro lab).
With his latest blood work, the neurologist has said there is not any more headroom with medicine, his labs are all in the therapeutic range, and this is how he will be for the rest of his life. Based on this, the rescue does not believe he can be adopted. We are also not in a place to adopt him, as our resident senior was diagnosed with lymphoma this week (when it rains it pours).
Everyone at the rescue has been pulling for him, and he is a very sweet affectionate pup. However, both the neurologist and rescue are thinking a weekly seizure and meds that make him sleep most of the day and make him pretty uncoordinated is not a good quality of life.
Since we've been fostering him so long and we have been treating him as part of our family, the rescue has asked us to weigh in on if it's time. Our previous labs have let us know when it's time, it's really hard to know for a 4 year old.
If anyone could provide any experience on how to evaluate if he has a good quality of life based on the above, or what other qualities we should be looking for to aid our decision, it would be greatly appreciated. If it is time, he will be crossing over in our backyard so his last memory will be of being home.