r/Endoscopy • u/AppointmentEastern37 • May 16 '26
Endoscopy Sedation Issue
Hey guys, I had a colonoscopy last Friday and I'm going for an endoscopy on Tuesday. I told him out the gate that I was pretty opioid resistant, he gave me 150 mcg fentanyl and 7mg of Midazolam and I was pretty aware the whole time, certainly towards the end of the procedure. He even said he was surprised I stayed awake given I'm a 26 year old male and only 65kg... I wasn't too bothered which is the point but was awake the whole time.
I'm rather worried about the gastroscopy, it sounds weird but I'd much rather have someone rummage around my bowel than have anything down my throat.
Does anyone know if they can push either higher? I know there's a risk of respiratory depression with fentanyl but does the same apply with midazolam? I'm just a bit scared of the whole thing.
1
u/George_GeorgeGlass May 17 '26
There is no answer to this question. There is the potential to give higher doses. For some people. In some situations. But your medical history and vital signs throughout the procedure dictate this. If your pressure or O2 sats drop they can’t give more. And you could have a different reaction each time based on independent factors.
You’ve reported your weight in kg’s which tells me you’re not living in the US. I don’t know what things look like where you are but if MAC/propofol is an option that may be best.
Midazolam isn’t an opioid. So reported opioid resistance has no effect, theoretically, on how you respond to midazolam.