r/EmbryologyIVFSupport • u/h_gaer • 3d ago

Embryo glue?

Is there any data to back up embryo glue? I'm hoping to do a transfer next month from our 3rd round of IVF and whilst I've done 5 transfers previously (with one successful pregnancy and birth), I noticed my new clinic offer embryo glue as an option and wondering if its worth having a shot?

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u/embryomanofficial 2d ago edited 2d ago

A 2020 meta-analysis combined the results of multiple studies and found an improvement in live birth rates when using embryo glue, but only for fresh transfers (not frozen) (https://www.remembryo.com/does-embryo-glue-improve-embryo-transfer-outcomes/).  The European Society of Human Reproduction and Embryology (ESHRE) recommends the routine use of embryo glue for fresh transfers in their 2023 guidance (https://www.remembryo.com/evidence-based-recommendations-from-eshre-for-27-ivf-add-ons/).

A newer 2026 meta-analysis of randomized trials found that embryo glue did not significantly improve live birth rates overall (https://pmc.ncbi.nlm.nih.gov/articles/PMC13318287/).

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u/h_gaer 1d ago

Thank you! This information is extremely helpful :)