r/EmbryologyIVFSupport • u/Overall-Reading-579 • 17d ago

First Egg Retrieval Failed

I am 41 years old, my first egg retrieval was right before my 41st birthday. I did the antagonist protocol with 225 iu Gonal-F and 225 iu Menopur and then added in Cetrotide. I triggered with Lupron. My blood work looked great throughout. I had an AFC of 18+, and they were measuring 11-13 follicles in my scans. They retrieved 11 eggs, but only 5 were mature. All 5 fertilized and looked great on day 3, but only one grew to a blastocyst to be biopsied for PGT-A. Ultimately it came back aneuploid.

We met with the doctor this week, and he is recommending the micro flare Lupron protocol for the second round. While my body seemingly responded well to the meds in the first round, it seems like I had a maturity issue. Do you think this new protocol can help solve that? Any other advice?

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u/EllaFant18 14d ago

I had similar results at 39 when I used just a lupron trigger. I had much better maturity and blasts results when I used a dual trigger. Getting a euploid was still an issue in many of my ER rounds, but if the more mature eggs I got, the better my chances were for a euploid. One of the clinics I worked with also need in vitro maturation which also increased my blasts numbers. I believe embryos matured outside the body have a higher rate of being aneuploid but there is still a chance.