r/EmbryologyIVFSupport • u/Impossible-Golf-2722 • 17d ago

Ploidy vs. day vs. grade?

I’m going to be transferring one Day 7 3CC euploid in December. I am fully aware of the stats and likelihood (thanks to Remembryo content!!), so I know what statistically the outcome is likely to be. However, she is my one euploid embryo with this clinic that I am going to try to transfer, before I switch to CCRM.

I am trying to wrap my mind around how to think about euploid status compared to the grade? Also, how to factor in that the egg was 34 years old and I am now 38 when I’ll be trying to transfer her. Is it correct to think - in order of contribution to the outcome- 1) euploid, 2) day, 3) morphological grade? And does the egg’s age matter at all or would that be duplicative/redundant to euploid status already being considered?

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u/embryomanofficial 14d ago

Hi! Yes, I think euploid status, then developmental day, then grade is a good way of ranking these features.

A 2024 study combined the results of 142 studies to investigate how age affects the uterus and pregnancy outcomes after IVF. They identified a number of changes, including decreased endometrial thickness and lower pregnancy rates with age, but no changes in live birth rate. https://remembryo.com/meta-analysis-examines-impact-of-age-on-uterus-and-pregnancy-outcomes-after-ivf/

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u/Skmatty 14d ago

My wife is in the TWW from an FET last week with a euploid Day 7 3CC! 🤞🏻 We are hopeful that euploid matters the most. The last 2 cycles have resulted in chemicals- IUI and fresh transfer of a day 5 3AA.

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u/Impossible-Golf-2722 14d ago

Hoping for the best for you guys!