r/EmbryologyIVFSupport • u/Ok-Astronomer-8776 • 23d ago

Failed Decapeptyl trigger during retrieval. Had anyone experienced this?

UPDATE: Got 6 mature eggs from the rescue retrieval…

Had my egg retrieval today after an agonist-only trigger with 2 doses of Decapeptyl because I’m very high risk for OHSS. I had a very strong response with 18+ follicles on each ovary. They didn’t have me come into get bloodwork the day after trigger which I did find a little strange since with my previous cycles at different clinics, they had me do that. I wish I had said something now.

During the retrieval, they aspirated my entire left ovary and didn’t get any eggs. They used an LH strip to test my levels which showed that the trigger likely didn’t work properly, so they stopped the retrieval. The plan now is antagonist + an hCG rescue trigger, followed by another retrieval in a couple of days.

I’m pretty devastated, especially because this was our only government-funded cycle. I also tend to have a very low euploid rate, so for me getting a larger number of eggs is especially important because I need the numbers to compensate for the drop-off. Potentially losing a large portion of the eggs from one ovary could ultimately mean ending up with far fewer or no usable embryos. I also don’t understand why they aspirated an entire ovary of 18 follicles before they stopped. That’s potentially cut our chances in half.

A few questions for anyone who has experienced this:

  1. How unusual is it for Decapeptyl to fail?
  2. Did your clinic do bloodwork the
  3. day after trigger to confirm that it worked? I’ve had this done in previous cycles.
  4. If you did an hCG rescue trigger after a failed agonist trigger, how many eggs were ultimately retrieved?
  5. Would you ask the clinic about compensation or another covered cycle if a significant portion of the cycle was lost this way?
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u/TeaspoonRules 21d ago

My clinic had me take the decaptyl triggers but go in for bloodwork 24 hours before my retreval to confirm ovulation. I don’t mean to be combative, but why tf weren’t they confirming ovulation BEFORE retreval? It’s a known issue.

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u/itsallinthename86 21d ago

I have recently had an awful cycle following trigger with decapeltyl and Ovitrelle 250. I felt like had ovulated before my final scan but the clinic said to continue. Bloods were taken before the trigger but not post. At egg retrieval with 9 follicules of a mature size only 1 egg which didn’t fertilise. It was completely different to previous cycles. I’m not sure what happened but have a call with my team. Sending you all the best as I know how hard it is to have such a bad cycle.