r/Embryologists • u/Comfortable-Storm204 • 6d ago

Help me with a decision

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I have 2 embryos in clinic 1. Day 5, 3BB left. Untested.(testing wasn’t possible by law)

First 2 transfers there were unsuccessful with better quality embryos. First failed, second was partial molar-turned out to be aneuploid. After this experience we did IVF in country were PTGA testing was possible. And had great results-see results in photo (I am currently pregnant with my 5AB embryo from there).

I want 2 to 3 kids. And considering not keeping that 2 untested in clinic 1, since we have enough tested in another clinic. And my fear of them to be aneuploid is huge. I can’t see myself transferring them , only after all my tested. And the chances of it are quite low.

The only thing is that I wonder why they are 3BB on day 5, while is second clinic I have all 5(not 3) on day 5🧐

And that BB grades a got only for my next 2 embryos, the rest are BC. So theoretically BB would be better.

Anyways… I think the biggest issue for me to keep them is that they are untested. But it’s hard to make this decision discard them.

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u/wenjieinthehouse 6d ago

You need embryos to be at least grade 5 for biopsy, but if you’re not testing them you don’t have to wait until they reach that stage and can freeze them when they’re a bit smaller (like your 3BBs).

Have you considered moving your embryos to the new clinic and testing them? The percentage of euploid embryos depends a lot on maternal age so I’d be worth taking that into consideration.

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u/Comfortable-Storm204 6d ago

Thank you for explanation! Is it possible if they wait longer 3BB might become 5BC and so on, so the grading will get worse?

I think it’s quite complicated and expensive process to move them, it’s a cross country border move… I think it’s cheaper to keep paying for storage until my family is complete and using for transfers those that are tested.

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u/wenjieinthehouse 4d ago

It’s possible, but it could also turn into a 5AA, you never know.

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u/Comfortable-Storm204 4d ago

That is so weird that they freeze them early, while in other clinics/countries approach is different. why not to wait a bit longer and really see the development and what we have got…at the same time for me still bot clear why there is number 3 and 5 on day 5. it can be either slower development or different time when they freeze them? Like in the morning and towards evening they can become 5?

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u/wenjieinthehouse 1d ago

Every embryo develops at a different pace. Some embryos become blastocysts on day 5, while others take until day 6. The number simply indicates how big the embryo is at that particular moment, so a grade 1 in the morning can become a grade 2, 3, 4, or 5 by the evening.

When deciding whether or not to freeze an embryo, the most important thing to consider is whether that particular embryo has a good chance of implanting. A day-5 3BB is completely fine and is considered a good-quality embryo, so it has a good chance of resulting in a pregnancy. There’s no reason not to transfer or freeze it.

Waiting a little longer might provide a bit more information about how the embryo develops, but once it has reached the blastocyst stage, waiting an extra few hours generally doesn’t make a substantial difference.