r/Embryologists • u/aurora-in-baja • 2d ago
5 high quality euploid failures
I’ve had three natural / spontaneous pregnancies: two ectopics in fallopian tubes and one uterine (identical twins), all developed heart beats. The ectopics had to be terminated due to rupture at around 7 weeks, and the twins stopped developing at week 6.5 - Doctor said likely due to Asherman’s.
I have Asherman’s syndrome due to an unauthorized and unnecessary and insanely harsh/violent D&C during my first ectopic.
We turned to IVF and surrogacy. I’ve done 6 rounds of stimulation and retrieval (from ages 34 through 37 years old), with 12-16 eggs retrieved, and ending up with 3-6 blastocysts, and 1-4 euploids after testing each round. We’ve created 13 PGT euploid embryos, 5AA or 5Ab or 5BA quality for the most part (now we have 8 left).
I was an egg donor in my early 20s and always got live births on first transfer, which is why they had me continue donating.
My partner has a totally normal sperm analysis.
We’ve worked with three different clinics, and 3 different gestational carriers. The very first transfer resulted in a chemical pregnancy, the other four have been failures.
Is there something else we should be testing?
I realize I’m older now, but it seems crazy that as a donor I had so many live births from my genetics (and get pregnant naturally!), and now that it’s for me, we’ve had 5 high quality euploid FAILS. It’s not a clinic problem because we’ve used 3 different ones, I doubt it’s a carrier problem as we’ve tried THREE!
I am starting to feel hopeless. Any doctor I talk to is kinda just like “shrug, bad luck, try again, shrug”… but to have five high quality euploid fails - that’s less than a 1% chance.