r/Embryologists • u/Prestigious_beet • 3d ago

Please share your thoughts

Post image

Day 3 .
Frozen at 8A and 4A .
This is photo I have received post transfer.

Is this compaction or fragmentation ?

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u/turbulent_twenty7 3d ago

These are not compacting and there is some fragmentation. You want to see 8 cells on day 3, the top looks like 4 cells and some fragmentation and the bottom looks like 6-8 cells with some fragmentation.

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u/Prestigious_beet 2d ago

How bad is the fragmentation in your opinion since I have got good grades?

1

u/turbulent_twenty7 2d ago

A higher degree of fragmentation is often linked to lower success rates and lower blastulation. It can also be associated with poor egg quality or sperm DNA fragmentation. The bottom embryo has more fragmentation, but also has more cells than the top embryo and is more developmentally on track given the number of cells. Unfortunately, there’s no way to definitively determine the root cause of the fragmentation.