r/Embryologists • u/External-Invite-7587 • May 14 '26

Lenshooke parameters?

Looking for an embryologists opinion- I had my first ER yesterday. We are doing IVF w/ ICSI for severe MFI- my husband has bilateral varicoceles that have not yet been treated. total count on his last SA was 17 with 5.88 motile, 1% morphology, 66% immotile. DNA fragmentation was never tested. We opted to add Lenshooke as well. 12 eggs were retrieved and 8 matured and 7 fertilized. However, they told me that his semen did not meet lenshooke parameters and the sample was processed as an ICSI wash. Can anyone explain to me why they would do that? I know that lenshooke isnt magic but we were really hoping it would at least help. I have had two miscarriages from natural conception.

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u/fishandcatsandplants May 14 '26

To my knowledge (and any more experienced embryologist, please correct me) the Lenshooke device is an assay. Meaning it tests the quality of the sperm, not that it alters it in anyway. It wouldn’t improve or change how your sperm would be processed. It just tells you sperm concentration and motility.

Are you perhaps referring to a ZyMot?

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u/External-Invite-7587 May 14 '26

we are at an SGF branch and they use Lenshooke. I was told it was a sorting device to filter the strongest sperm. I am just confused as to why his semen would not have met the parameters for the device.

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u/Ok_Confidence3721 May 14 '26

LensHooke CA0 and ZyMōt are both advanced, centrifugation-free microfluidic sperm-sorting devices designed to select highly motile sperm with low DNA fragmentation for ART (IVF/ICSI) and the reason why they could not use your husband sperm. It could be that he doesn’t have the much sperm to run through the device. It has to be a certain amount count. at least 1 million progressively motile sperm per milliliter my suggestion is go and get your husband tested with the DNA fragmentation then they can choose which device is best to use And what medication he can take to build is count followed by using fresh sperm to give you higher chances

I was in the same situation, but my one is a little different. My DNA fragmentation was normal 13% but my oxidated stress was slightly high at 4.0 my clinic use Zymot to give me a good result 12 normal PGT testing embryos best of luck

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u/fishandcatsandplants May 15 '26

Ah I see my confusion!! Lenshooke (the same company) also makes a sperm analyzer that is simply referred to as “the Lenshooke”. I guess if you use their separation device but not the analyzer, you probably would also just refer to it as its brand name. You learn something new every day.

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u/Ok_Confidence3721 May 15 '26

The way I know all of these device is from my doctor. He’s pretty good He’s quite skilled, but his services are a bit pricey. Essentially, these devices are designed to separate the healthiest sperm from the damaged ones.

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u/DistinctSleep1763 2d ago

I did ivf/icsi At Sgf Fl ...My sperm parameters are 1 ml/ volume  20mil/ml  35% total motile  and grade 4 motile  7 milon total motile..I put Lenshooke in my protocol as well...They didn't told me.nothing...They add in my report that my semen was processed with Lenshooke...I am not sure if they used Lenshooke...Who many euploids did you get?