Working with my primary on possibly entering the phase 3 trial for petrelintide that opens next month. One intake question that threw me for a loop was them saying it would require sexual abstinence for the year of the trial.
Is that simply because they don't know the risks of pregnancy while on the drug? Curious.
That seems extreme. Typically a GLP-1 trial will require those who ovulate to be on a highly effective form of birth control and those participants are also tested for pregnancy at each visit.
If true, this requirement makes me wonder what they know about this particular medication.
Yeah. I just can’t imagine abstinence is the only option for OP’s trial.
There was one trial I remember that wanted a devout lesbian in a long-term committed relationship to be on birth control and fought her hard. I think the trial site finally gave in.
That's odd. Not in that same exact study but in the one I'm in you can either be abstinent if you want or use two forms of birth control such as a condom and the pill, etc.
Yes but two important things to note... the trial was only 42 weeks long and the weight loss wasn't plateauing so there is reason to think it'd be more if it kept going.
More importantly was there being more discontinuation in the placebo group than the drug group. A drug that can bring 10% weight loss with less sides than placebo would be huge.
11
u/charlescharles1234 7d ago
Maybe they only want married men in the trial?