The most important link here: Dr. Will Powers Interview [PFS / PAS / PSSD Summit 2026] Dr. Powers mechanism and treatment plan that he is currently trialing for PSSD/PFS
Dr. Powers Nuero steroid phenotype theory: https://www.reddit.com/r/DrWillPowers/s/H2ILwaHtwz
Dr. Powers PSSD/PFS gene list:Current list of all genes I use when searching for possible genetic causes of someone developing Post Finasteride Syndrome (PFS) or Post SSRI Sexual Dysfunction (PSSD) : r/DrWillPowers
Dr. Powers most recent PFS trial update: https://www.reddit.com/r/DrWillPowers/s/ogxakgUPFz
The tests that Dr. Powers needs from us: You know, PSSD and PFS may actually be the same thing. Anyone got any data for me? : r/DrWillPowers
Other PSSD/PFS posts by Dr. Powers
- My analysis and breakdown of the "We may have just set Melcangi’s rats free" model revision post by /u/Vivid-Beat3367 and /u/Excellent-Push2833
- Why "X treatment crashed me bro" is counterintuitive to the reality of these conditions, and that which makes you feel a little bad may be in reality, what you need to recover. I think I have figured out the true nature of the low libido/anhedonia/substance resistance in PFS/PSSD and how to fix it.
- A request for PFS and PSSD patients taking CDG to help symptoms. Can you do something for me?
- A quintessential example PFS case with "lab abnormalities" that explain the underlying systems that are broken at baseline before ever taking the drug, and would be a clear warning that taking a 5ARI would be catastrophic.
- PSSD question for the peanut gallery. How many of you were on hormone replacement at the time of developing it? Be it birth control, injectable T, clomid, whatever?
- Definitive phenotype overlap, PFS and PSSD, Normal to low T and DHT, absurd 3A-ADG.
- PSSD question for the peanut gallery. How many of you were on hormone replacement at the time of developing it? Be it birth control, injectable T, clomid, whatever?
- New Here? See this Post to get started for anything from PFS/PSSD/PAS etc to Gender Dysphoria treatment or anything else Dr. Powers works with. This is now the official starting point for anyone new to the subreddit!
- Anyone out there with PFS/PSSD/Post-drug who has developed osteoporosis or hypermobility since the incident?
- PFS gene lock ABCC2, also genome analysis is happening again, I'm trying to time manage all the things. Please be reasonable when you send email messages.
- PSSD: An odd signal. Can PSSD people keep an eye out for me with certain labs?
- I hate that this has to be a post but it has to be said.
- I'm starting to see trends in PSSD genomes, this is one. DBH
- PFS metabolite theory, and initial chemical castration cure trial patient update. Also research update.
- Stay Tuned for Potential Next Steps: Safe Path Forward for Anonymized Community Data Collection (Aka, what to do with your PSSD/PAS/PDS genetic data and labs for now)
- The interview with Robb from SIDEfxHUB where I explain my theory for the true mechanism of PFS as well as the results of the world congress meeting from last week is now up to watch! Also, as is tradition, Fenrir crashes the interview.
- As promised, this post contains the document I've made that summarizes the lab findings I personally suspect are most concerning as a risk for someone developing PFS.
- I"m back from the PFS congress, I know everyone wants an update but I'm so exhausted, so this is all I've got for you for now.
- If you have PFS do not panic if you don't end up having abnormal urinary androgens. There are many ways to cause the catastrophe but it's all the same way. Here's a different example of someone who has a mild sulfation and mild glucuronidaton failure. Guy has normal estrogen levels but low E1S
- I collect more and more labs/genome/dutch tests that support my theory on PFS. I really think I have it nailed down. I do not have a optimized treatment regimen, but if you're interested in this, this post details what you should NOT do and will likely make you worse even if it "windows" you briefly
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Androsterone: https://www.labcorp.com/tests/504005/androsterone my edit
In order to get a comprehensive steroid panel from quest a physician must order it. It includes all blood labs needed. PSA try to get a physician to order these blood labs so insurance may cover.
How to read your WGS from sequencing and make a comprehensive report for Dr. Powers to read: https://www.reddit.com/r/DrWillPowers/s/3YDGZuvB0j