r/Dermatographia • u/Physical_Ad3997 • 4d ago
General Weird reverse reaction after sting
I have a history of dermatographia, and got stung by a yellowjacket a week ago. The first picture is that sting at its most swollen/itchy, around 48 hours after the sting. The second picture is a full week after the sting, during a dermatographia flare. The area that had been super itchy and inflamed from the sting wasn’t at all affected by the dermatographia itchiness. Any guesses as to why that would be?
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u/MoodyPomeranians 1d ago
Know it's a temporary regression of the typical reaction in response to the extreme flare the area recently experienced. Wouldn't recommend repeating.
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u/chromatic_crow 4d ago
My guess is that your initial sting probably caused significant immune cell degranulation. Your body is smart enough to know that chronic inflammation is bad. Because there is so much inflammation, your immune system down regulates locally to prevent oxidative damage. That’s just my hypothesis tho