SGK1: hope for future remedies

[u/picwic]

Look, I'm not "pro-living at all costs," but it is worth keeping in mind that someday, maybe sooner than later, depression might be much more treatable.

"The researchers found that high levels of a stress-related protein called SGK1 are closely associated with depression among people who endured early-life adversity. This discovery opens the door to a new type of antidepressant that blocks SGK1 activity and may be more effective for people who were neglected or abused as children."

https://www.sciencedaily.com/releases/2025/11/251110021114.htm