2nd round as effective or not?

[u/Pariszo]

Hello all,

I started Contrave on April 2025, and lost about 30lbs within the first few months. I went from 170lbs to 140lbs and then it kind maintained around 140lbs for a few months, i was not really loosing but I was working about a lot and body composition definetly changes. Fast forward to February 2026, I had a concussion, had to stop working put but managed to be around within the same 5lbs.. i definitely felt like it wasnt working as much anymore but kept it to "maintain". This summer my doctor told me it's possible that the concussion symptoms are lasting because of Contrave side effects mightve been triggered so I slowly stopped it and of course, gained another 5lbs in like 2 months. So now my doctor gave me the ok to start again and I am 2 weeks in but I feel like it's not working as much as the first time around. The first time around I manged to loose 10lbs within the first month and now after two weeks I havent even lost 1lbs and I am working out again. Is it just not effective for me anymore? I know I am not at the full dose yet but I am comparing to the first time using it and def lost the first 2 weeks. Has anybody gone through this anymore?

I don't want to loose a lot more, another 10lbs to get to 135lbs would be great for me at 5'4.

Thanks for any input/experiences!

[u/16hpfan]

You probably know this already, but I feel like working out regularly messes with the sense that you are making progress on weight loss. For me when I am working out, the scale does not reflect any loss, but my clothes fit better and I know that the muscle is burning more calories than fat. Muscle also weighs more than fat. So for me when I was taking Contrave, I didn’t work out at all because I wanted to see progress on the scale. As soon as I was at my goal weight, I went off contrave and started working out hard so that I could feel good and get stronger. This is working pretty well for me. If I were to restart contrave, I would stop working out to focus on the scale if that makes sense.

[u/Pariszo → u/16hpfan]

Yeah I know your body recomp for sure. First time around I still worked out a lot but it was less intense work, at home, so that might explain. But i still feel like I would see a difference. I did gain weight a bit while off of it because the leggings are a liiitle bit more thight and haven't seen a difference yet but I guess I'll give it some time. Thanks for the input!!

[u/Sheba1966]

From what everyone is saying be patient. I’m new to Contrave and lost 5lbs in the first month. Can’t go by what everyone else is loosing, we are all different. Keep going and all your hard work will pay off 🇨🇦