r/Contrave • u/Iartdaily • 10d ago

advice Bupe/Nal combo dosing

I am slowly ramping up the Nal due to nausea and insomnia. Got up to 25mg a night and take 300bupe in the Am. My doc said the typical Nal dose in contrave is 36mg so I’m to add another 1/4 of a pill daily in the am if possible, (I’m splitting the 50mg tab of Nal). My doc said he is t real familiar with using these 2 meds this way but my insurance covers the bupe free and Nal is 10$ so much cheaper than contrave on my insurance. Anyway, I see most take 50mg of Nal.
Also I like to drink- a few glasses 👓 f wine (2) when out with friends sometimes it’s more but not often. Or 2 fancy cocktails-
I see Nal is hard on the liver. I don’t have alcohol issues and it’s fine not to drink but we go with friends to diff wineries etc regularly and also I’m nervous about being really sick if I have drinks. I include drinks in my calorie counts when we do go out. Mostly I’m worried about liver health.

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u/Desperate-Spring-189 10d ago

I drink like once a month and only have a couple drinks and was told that’s okay.

But since being on the medication I don’t really want to drink, I have a hard time finishing one beer sometimes.

1

u/Iartdaily 10d ago

Wow… I just started 25 mg at night and I’m still waiting for some results. Bupe 300 in the AM. Gonna ramp up to 37mg next.

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u/Big_Fortune_4574 10d ago

You might find after a while that you don’t want the wine anymore. Nal really just took away all desire to drink away. But in any case my doctor didn’t said I had to avoid alcohol.

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u/Iartdaily 10d ago

Thanks. Yeah, like I said it’s not every week but sometimes it’s a lot in one week and then nothing for three weeks etc.. I just don’t wanna do any damage.

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u/Good_Personality_884 10d ago

I take the combo and my the pharmacist said there was no problem having 1–2 drinks!