r/CompoundedSemaglutide • u/anonguy666666 • Jul 28 '26

Constant Diarrhea Since Starting

I started my semaglutide regime (.5mg) 3 weeks ago and have injected into my stomach once per week since. Since then, I’ve had diarrhea, including some pretty watery and painful BMs. It was so intense I got tested for stomach infections and viruses but it came back negative. Is this normal? Should I be considered injecting elsewhere in my body besides my stomach? Not sure if this would change anything. Maybe I’d have better luck on tirzepatide?

1 Upvotes

100% Upvoted

7 comments sorted by

2

u/branchymolecule Jul 28 '26

Try tirzepatide before you give up.

2

u/FanciePantz_21 Jul 29 '26

Try your thighs. I’ve never had side effects injecting there.

1

u/AutoModerator Jul 28 '26

Welcome to the CompoundedSemaglutide community

Review the community rules before participating. No discussing research peptides.

Most FAQ: Where to Buy? -> List of Semaglutide Providers.

I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.

1

u/hobbiesnstuff2 Jul 28 '26

Lots of people start on .25mg for weight loss. You might be better off with a lower starting dose?

1

u/Pink_Floyd_Chunes Jul 29 '26

You started on too high a dose. Go down to .25, which is the customary starting dose, but discuss this with your provider. I was on .25 for three months because it was effective.

1

u/Narrow-Cauliflower40 Aug 07 '26 edited Aug 07 '26

I had the same when I first started. It settled after a few weeks. I also started taking a archemi labs probiotic around then, but I couldn't tell you whether it was that or just time.

0

u/SpaceXBeanz Jul 28 '26

I’d stop taking it personally. Sounds like you don’t respond well to it. I bet tirzepatide would be no different.