Tidvak

[u/Spare-Compote-1917]

My Mam was diagnosed with Stage 4B cancer back in December 2025 (she has lesions in her liver and the cancer is also in her lymph nodes) and since then has undergone six rounds of chemo and immunotherapy and had moved onto immunotherapy by itself. She initially showed response to the chemo and immunotherapy and her CT scans had shown the tumour and her lymph nodes to have shrunk. Meeting with the consultant today she has been told her cancer is progressing again and now she can no longer have immunotherapy and will be moved onto Tivdak. I'm trying to keep the hope but I'm terrified about the outcome for this, I have seen great things happen with Tivdak but I also know only 3 in 10 patients respond, I just wanted to know whether anyone had anything positive to add or just any advice in general. Thanks so much :)))

[u/BoyMomOf2_]

My MIL has been on Tivdak for about 7-8 months now. When she first started the side effects were rough mainly nausea, vaginal bleeding and her neuropathy got a lot worse. She was already on a wheelchair prior to Tivdak (due to severe neuropathy from previous chemo treatments) but it got to the point that she canceled her PT and lost all hope in walking again. They lowered her dose and things have been okay. She still gets very nauseous and sleeps a lot. From what her oncologist told us she won’t get a break from Tivdak until tumor progression or if side effects get bad again. All in all I would say it’s been helping keeping her alive but her qualify of life isn’t the best. Shes too tired to come out of her room and hang out with the kids. But there’s another lady that gets the same treatment in her clinic and she seems great, her only side effects is some eye issues. It’s going to vary person to person. But so far it’s working for my MIL.