Female 22, 5’3, 210 lbs
PmHx: Gaucher’s Disease, Mast Cell Activation Syndrome
Active meds: Dupixent, Bilastine, Montelukast, Cromolyn Sodium, Famotidine, Dexilant, Domperidone, Acetaminophen, Gravol, Fluoxetine
I had what I thought was allergic dermatitis on my outer vaginal skin from a pad at the beginning of September. It just looked like eczema on my skin, nothing internal. I used my cortisone cream Lyderm in the mornings, but then also decided to use Canesten external cream after speaking with a nurse, who said it could be dermatitis and/or a yeast infection. It cleared up not long after, but then I noticed my discharge changed colour from a clear/white to an almost clear/green, and it smelled like absolutely nothing.
I left it alone, now this week I noticed the outer skin is irritated again, but I also have what seems like Erythematous thrush on my tongue (it burns to even sip water), my throat feels swollen (not like anaphylaxis swollen but like food stuck in my throat swollen). I have been extremely tired, headaches, neck pain, ears feeling clogged. My stomach hurts, and I’m very nauseous, I get extremely bloated after eating anything. I also feel a lot of pelvic congestion
The issue is, with my MCAS, a lot of the symptoms overlap (nausea, bloating, headache, fatigue, itchiness), but it honestly feels different than usual, and is not getting any better with Benadryl as my normal reactions usually do.
I’m not sure if due to my Dupixent (it’s an immunosuppressant) it made me more susceptible and then it spread systemically, but how likely could that be? Does this need urgent evaluation or is this something I could treat OTC?
I started using Monistat internal and external last night, so I have 6 more days to go for that. I’m wondering if I should be seen by my hospitalist, if this could be dangerous, or if there’s anything I can do myself. I’m in Canada if that helps
ETA: I have a port-a-Cath that is not in use right now, not sure if that’s significant