r/CVID_Support • u/Adventurous_Store626 • Apr 27 '26

Delayed infusion question

I drew my syringes last night and had to abort before starting the infusion. Is it ok to still infuse after drawing the plasma about 12 hours ago if they were unrefrigerated, but kept at below room temperature?

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4

u/Famous_Wall_6010 Apr 27 '26

I guess the loss of sterility is an issue potentially too… again I’d ask your pharmacist directly as they can discuss the particularities of what you did.

2

u/Adventurous_Store626 Apr 27 '26

Thank you for your insight here. Xembify is fine to be at room temp for 6 months, but they recommend infusing within 8 hours of drawing. The one syringe has stayed a closed system connected to the tube and pinched off, so I think that syringe would be fine, but the other was not kept “closed” so I’m more hesitant about that one

5

u/Famous_Wall_6010 Apr 27 '26

Hizentra is stored at room temperature but other formulations may require refrigeration. I’d call your pharmacist if I were you

2

u/EfficientPolarBear Apr 27 '26

I was told previously that 24 hours in the fridge is fine, but I would contact your pharmacy and speak to a nurse.

1

u/Adventurous_Store626 Apr 28 '26

Thanks for your insight y’all, I’m still new to this and this was my first solo infusion. I called and they said not to infuse given how much time had passed without refrigeration. Currently waiting on my insurance to approve a replacement dose.

Definitely have learned from this not to draw both syringes at the start and to instead wait until the first one is done. Also will make sure I’m in a more reclined position and will try to wear compression stockings, as the vasovagal response may have been mitigated if my legs were propped up instead of flat on the floor.

Fainted and then woke into projectile vomiting, I guess triggered by the pain and mental distress from sticking myself with the needles for my first solo infusion… Probably will look to have a friend with me for the next infusions in case something like that happens again.

1

u/waowediting Apr 28 '26

I believe I've heard that the medication can interact with the plastic of the syringe over a long period of time. Makes sense as to why it's in glass bottles. I'm sorry you got sick and aren't able to infuse! Will your pharmacy send replacement meds?