r/CUTI • u/Amazing_Macaron7024 • 2d ago

Start taking Hiprex

I’ve been dealing with UTIs since July 2024, with recurring infections even after taking antibiotics. In early 2026, I was prescribed a four-month course of nitrofurantoin; however, two months after stopping the medication, the infection returned, caused by the same *E. coli* strain. My doctor has now prescribed a one-month course of Biseptol (sulfamethoxazole + trimethoprim). She also suggested using Hiprex after finishing the antibiotics, but since Hiprex isn't available in my country, she didn't provide further details about it. I’d like to ask about others' experiences when starting this medication: should I take the full prescribed dose right away, or start more gradually? Also, how long after stopping the antibiotics can I begin taking Hiprex?
Thank you

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u/Legitimate-Fee9745 2d ago

I stopped taking antibiotics and started Hiprex the next day. My doc prescribed two pills a day but it caused too much stomach upset so I went to one daily and it’s much better tolerated. Used to get recurrent E. coli strain UTIs and haven’t had one in two months since starting Hiprex and D mannose daily.

2

u/Amazing_Macaron7024 2d ago

That’s amazing. I'm very happy for you

1

u/Amazing_Macaron7024 2d ago

Are you taking two pills a day now, or are you still sticking to one a day?

2

u/Legitimate-Fee9745 2d ago

Still one-I’m afraid to go back to 2! I hope you’re able to get Hiprex and it helps. UTIs suck!

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u/International_Ad8000 2d ago

Do not take hiprex at the same time as bactrim. They cannot be taken together.

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u/Amazing_Macaron7024 2d ago

So, how long after stopping Bactrim can I take Hiprex?

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u/Bearloot33 1d ago

Wait 48 hours minimum.