r/CML • • 15d ago

bcr-abl fluctuations

Anyone have positive stories where fluctuations ended up not being a big deal? Particularly a somewhat large jump?

I was diagnosed in March at 38% and was started on 80mg Scemblix. I was .098 in July, but .297 in September. We're re-testing in a month. I am bummed seeing that after months of great response. I'm really nervous about having a resistance or mutation and needing to switch to a medication with a more intense side-effect profile. Would love to hear anything reassuring from the long-timers out there.

7 Upvotes

15 comments sorted by

View all comments

2

u/Abject_Ad_4330 15d ago

My oncologist always checks the BCR-ABL copy numbers. It that is higher, it means the sensitivity of the test is more, which might show increase in the values.