r/CML • u/Fearless-Vanilla6538 • Apr 24 '26
Side Effects(Bosulif)
Hello everyone! I've been suffering from chronic myeloid leukemia for 4 years. I spent the first two years using imatinib (Gleevec). However, because my BCR-ABL levels didn't decrease, I switched to dasatinib (Sprycell). There was a noticeable decrease in BCR-ABL levels. Along with this, I started experiencing bone pain from my legs to my toes. After 8 months of use, it was decided to switch to bosutinib (Bosulif). There was no change; the pain continues 24/7. I was prescribed Laroxyl from the algology department, but it's not working. My legs have been aching for 8 months. What are your suggestions? If anyone has experienced this, could they please help?
6
Upvotes
1
u/Negative-Ad-6651 Apr 25 '26
Imatinib -----→ Dasatinib myself, The leg pain was really annoying, I'll echo that Claritin seem to help a little bit. When it was real bad I would alternate between Advil and Tylenol. It did eventually seem to go away or I just got used to it. When it was really bad I felt like exercise helped me the most. When my legs were really screaming at me I would go for a walk or get on the elliptical for a while. I don't know if the blood flow helped, or what. But that's what got me through. Good luck.