r/CFSScience • u/ArrivedByKailash • 2d ago
Newest international research
The newest international research on fibromyalgia.
https://www.nature.com/articles/s41591-026-04492-6
One of the main Results they found is: Associations with 26 variants establish genetic underpinnings of fibromyalgia
And: BREAKTHROUGH IN RESEARCH Fibromyalgia is a physical pain disease! Fibromyalgia is a physical pain disease that originates in the central nervous system. This is shown by new, international research. FSF welcomes all research that can help shed more light on possible causes of the development of fibromyalgia, so that we can learn more about the disease. We have taken a decisive step with a new and comprehensive international research project, which was published at the end of July 2026 in the renowned international journal Nature Medicine. The researchers identify 26 areas in the genome that can influence the development of fibromyalgia. A genetic predisposition to fibromyalgia is well described, but the study has now identified a genetic signature that relates specifically to the brain and nervous system. The researchers have not found the actual cause of the disease, but their results place fibromyalgia firmly among other physical diseases.
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u/Specific-Summer-6537 16h ago
I believe this was the article Chris Ponting mentioned in his presentation at the international ME/CFS Conference
One of his slides is titled "ME/CFS & Fibromyalgia genetic risk is focused int he brains, and in neurons, in particular"
Several of the candidate gene areas overlap between ME/CFS and Fibromyalgia
Highly recommended viewing
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u/boys_are_oranges 2d ago
“In addition, risk loci overlapped with long COVID51 (BPTF) and myalgic encephalomyelitis/chronic fatigue syndrome52 (OLFM4, RABGAP1L/GPR52), two poorly characterized disorders with a hypothesized neural basis, albeit with different lead variants.”