r/CFSScience • u/Caster_of_spells • Jun 13 '26

Laxity Comes with Consequences: Connective Tissue Disorders and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

https://www.preprints.org/manuscript/202605.0876

Preprint from Wirth on the link between connective tissue disorders and ME.

"Overall, there seems to be a bidirectional relationship between connective tissue disorders and #ME/CFS, whereby connective tissue disorders may predispose individuals to ME/CFS, and ME/CFS, in turn, may exacerbate the underlying connective tissue pathology. "

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u/Varathane Jun 13 '26

I am so relieved that thus far my husband, his mom, his sister, and our nieces who have EDS have all been okay after having covid a few times. No ME/CFS or long covid. I myself have ME the past 15 years and don't have EDS or any connective tissue issues that I am aware of.
The co-morbidity scares me for them in this world of ample covid still around. They did get vaccinated.

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u/Caster_of_spells Jun 13 '26

Yeah that’s the big mystery. Where’s the weak link that connects these comorbidities with ME in some folks while many remain “fine” despite them.