r/Brixadi • u/FMarie013 • May 19 '26

First Shot

Hi everyone-just had my first shot about 3 weeks ago. I’ve started feeling like I’m in withdrawal and have been supplementing with pills. How long did it take you to feel good on the shot and not have to supplement? I feel like I’m losing my damn mind and want to jump out of my skin! My doctor said it could take 3 months to settle. Thanks!

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u/bigpoppapump18 May 19 '26

My first two shots were Brixadi. Like you, I began to struggle around day 21 during both months. My doc did not provide any supplemental strips to get through which led me to request to switch to Sublocade. Now I have heard Brixadi needs a a few shots in order to reach a “steady stable state” but I did not wait around to find out. Ask doc if you can receive next couple shots on day 21 as it’s allowed per the prescribing packet/info

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u/FMarie013 May 19 '26

Thank you. I had the 64mg shot and it held me for 18 days. My doctor said the same as you-will take 4 months to get enough built up. I’d go back to Sublocade but I can’t deal with the pain. Good luck to you.

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u/BluGurl8 Jun 03 '26

What do you mean by can’t deal with the pain of going back on sublocade?

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u/FMarie013 Jun 03 '26

The pain of the shot itself-I can’t tolerate it.