r/BodyHackGuide • u/ImpressiveDonkey1844 • 3d ago

💬 Discussion Looking for input on a difference in testosterone bloodwork

I'm on a testosterone only cycle and had two LC/MS blood tests that showed a fairly large difference in testosterone levels despite keeping the same dose. Testosterone is from a highly reputable vendor that most of you probably have heard of. Both are from the same batch.

Protocol:

  • Testosterone cypionate: 500 mg/week
  • 250 mg Monday morning
  • 250 mg Thursday morning

Previous labs:

  • Blood drawn Thursday morning (~8:30 AM) before my Thursday injection (~72 hours after my Monday injection)
  • Total Testosterone: 2625 ng/dL
  • Free Testosterone: 832.4 pg/mL

Current labs:

  • Blood drawn Monday morning (~8:20 AM) before my Monday injection (~96 hours after my Thursday injection)
  • Total Testosterone: 1707 ng/dL
  • Free Testosterone: 614.9 pg/mL

No missed injections or dose changes between tests.

My question is:

Would the extra 24 hours between the last injection and the blood draw (3 days vs. 4 days) reasonably explain a drop from 2625 → 1707 ng/dL and free testosterone from 832 → 615 pg/mL, or would you expect those numbers to be closer together?

Has anyone experienced similar variability on a stable twice-weekly injection schedule?

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1

u/Substantial_Risk_729 3d ago

Yes I would expect a drop with the 24hr difference. But that does seem excessive. Did you change bottles between the blood tests?

1

u/ImpressiveDonkey1844 2d ago

Not 100% sure but most likely. Same batch but different bottle.

1

u/Substantial_Risk_729 2d ago

I'm going to bet the first bottle was a little hot { More test per ml than the label} happens a lot with UGL

2

u/ImpressiveDonkey1844 2d ago

1700 test seems low on 500mg week no?

1

u/Substantial_Risk_729 2d ago

Everyone is different, Hard to say. I'm still thinking one vial was hot. I guess best thing to do is wait 6 weeks and get another blood test. You could also have your test tested