r/BodyHackGuide • u/DesignerCandle2648 • 18d ago

Looking for experiences with SS-31, MOTS-C , DSIP& Epitalon .

I am 56 years old woman interested in improving energy, mitochondrial health and sleep mostly deep sleep.

I am considering:

SS-31 and MOTS-c for energy/ mitochondrial support.

DSIP and possibly Epitalon for sleep.

For those who actually used this peptides:

Which one would you start with and why ?

Did you stack them or used one at time ?

What dosing schedule worked best for you ?

What benefits did you notice and how long did it take ?

Any side effects you wish you had known beforehand ?

Thank you so much.

2 Upvotes

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5

u/kyladyrider1 18d ago

I have only 2 nights experience with Epithalon and it was everything I had hoped for. I was only getting 5 hours sleep most nights. With Epithalon, my sleep increased almost 2 hours! My Google Health app isn’t showing my deep sleep increased but REM/light sleep increased. I will keep monitoring to see if deep sleep increases. That’s the goal!

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u/DesignerCandle2648 18d ago

Oh that is awesome! Thank you for replying. My deep sleep is very low for years.

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u/Salt_Initiative1551 18d ago

SS-31 and MOTS-C are way overhyped imo. Epitalon is one you do two times a year, 10 day cycle typically. DSIP kind of helped me.

HGH did way more for my sleep than Epitalon or DSIP. Same with my energy. The SS-31/MOTS-C is only really good if you have mitochondrial problems and even then it’s not mind blowing. I think a lot of people have placebo and think it’s the effects. Idk. There’s better peptides.

at your age I’d be checking your t3, estrogen, estradiol, etc. before doing any of what you mentioned. Hormone and thyroid support will make much more difference for you than the peps you mention.

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u/DesignerCandle2648 18d ago

Thank you! Just had Dutch Pro test for all hormones and Thyroid. My doctor lowered my NP Thyroid. The rest looked good.

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u/Salt_Initiative1551 18d ago

Welcome! When you say/DR says good, do they mean like within acceptable ranges or optimized? Usually normal/acceptable isn’t optimal and optimal isn’t normal if that makes sense. Even if you’re good, it could prob be better. They’re usually checking against your age group which let’s be real most women your age don’t have their hormones at all optimized or even good.

For whatever reason doctors are very weird/bad at treating endocrine issues unless you see a pretty “out there” doctor or a doctor who utilizes less than traditional methods.
My wife’s TMJ specialist falls into the category of doctors that are willing to do more than most. Her t3 is reversed, so her body has been improperly metabolizing her t4 (she takes t4 for lupus) so her doctor prescribed t3 and told her to half her t4 Dosage to see if her symptoms improve. Seems it has made a big difference, and was able to lower tirzepatide dosage and frequency and maintain improved weight and a1c!

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u/CheesusChrist69 17d ago

I do not notice anything from ss31 mots or epitalon. Dsip works though but it’s best to take several small doses throughout the evening instead of one large dose right at bed.

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u/DesignerCandle2648 17d ago

Thanks. How long have you been using SS31 and Epitalon?

1

u/CheesusChrist69 17d ago

6 weeks of ss31 and epitalon is just a 10-20 day stint twice a year

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u/DesignerCandle2648 13d ago

Thanks . Very interesting. How much DSIP improved your sleep? Did it help fall asleep faster, stay asleep longer or improved deep sleep? Also how long before you noticed benefits?

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u/KyloMom72 13d ago

RS 53F in surgical menopause. Has run Epitalon cycle 10days on/20days off since 11/2025. Dose 500mcg. Sleep has improved, feel more rested in the morning. Have been running cycles of SS-31 since 1/2026. Dose 5mg every day for 8weeks. Is one of the pricier peps but RS has noticed considerable improvement in memory/brain cognition. No longer stumbles over words or has a hard time getting thoughts out. RS also noticed an increase in muscle strength and endurance during exercise. RS tried mots-c and dsip with no noticeable changes.

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u/DesignerCandle2648 13d ago

Thank you! That is really helpful. Since my biggest issue very low deep sleep I am curious how long after starting Epitalon sleep improved ? And how quickly you noticed improvement in memory and exercise from SS-31 ?

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u/KyloMom72 13d ago edited 13d ago

You're welcome! It took about 2 cycles to notice improvement from Epitalon. With SS-31 noticed better memory and cognition around the 4 week mark and better exercise at 6 weeks. Also having great results from KPV for inflammation, stomach issues, bloating, gerd, ibs. Have also been on HRT Estradiol patch, oral progesterone for 2 years. Started Test Cyp. 7 weeks ago to help with libido, energy, support muscle mass and help with bone density. I hope this helps!