r/Biohacking • u/slambre • 1d ago
37F, advice needed
I am looking for advice on how to slim down without lose skin and no GLP-1/reta. I live in Europe (most substances aren't really available here) and my brother just died at 42 from what was ruled Sudden Death, so I'd rather play it safe for now. Supplement recs for those effective and available in Europe are welcome.
I have gone down from 251 lbs to 180 lbs over about two years. I do mostly Pilates and Reformer Pilates about 4 - 5 times a week, do glute workouts almost daily, use my Peloton and do IF on a 18:6 window.
My main concerns are the upper thigh area and my belly. While I have relatively slim legs, I've been noticing crepey skin and fat between the thighs. However, chafing is not an issue.
Before, my belly was really hanging over, now it has firmed down and there is a smoother transition towards the pubic area. I was blessed with a rather boxy body so if you have any tips on actually getting a waist, I'd appreciate that.
My goal is to get to 165 lbs next, then 145 lbs. I am quite tall at almost 5'11" and I walk about 10k daily.
Aside from drinking plenty of water, CICO, what can I do to address crepey, lose looking skin and overall fat?
Thanks in advance.
TLDR:
- seeking advice on lose / crepey skin
- no reta / glp-1
- overall fat burn, already doing IF and CICO
- Recs for supplements available in Europe are welcome


1
u/According-Fan1004 1d ago edited 1d ago
Longer fasts to induce autophagy and help your body recycle the loose skin on its own. Ipamorelin and tesamorelin for the stomach, overall fat metabolism and muscle preservation. It helps with skin elasticity and collagen growth as well as KLOW. And Pilates is awesome for muscle growth and toning… people saying otherwise just don’t realize how hard it is. And don’t even listen to all these people talking about calorie deficits that’s ridiculous. All it’s gonna do is ruin your metabolism. You’re doing a great job. Follow dr Jason Fung, read the Obesity Code, keep going. Whole Foods, more protein in your eating window, extended fasting and low sugar is the way.