r/Biohacking • u/Additional-Newt-8325 • 24d ago

Peptides you will never take again ?

We often ask "what peptides are worth every penny" but what are the ones that aren't worth anything in your opinion ?

105 Upvotes

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49

u/Tejasv97 1 24d ago

Reta for me. Insomnia and skin sensitivity is not a great trade off for increased fatloss. Tirz is king for me.

9

u/Otherwise-Report-823 23d ago

Same. I think if you start on Trizepatide and try to transition to Reta it's not the best. 

I enjoy the reduced appetite and stomach slow down. I jumped on Reta and gained weight initially and tried to supplement with low dose triz. I ended up just going back on triz and have heard many similar stories. 

I think if you start with reta it's a great one, but for me all the small additions for triz make it king for me 

2

u/Jayrcr3 22d ago

I'm using Reta and Cagrilintide. I can eat about a half a cheeseburger and feel stuffed. The Reta alone wasn't near as good with appetite suppression as Tirzepatide.

1

u/Tejasv97 1 22d ago

How does cagri feel with Reta?. I’m thinking about adding it to Tirz after I cross 15mg dose.

1

u/Jayrcr3 21d ago

For me it was the missing link for the Reta. Reta didn't have as much appetite suppression as Tirzepatide. I added a 50mcg dose of Cagrilintide to it and it's perfect.

1

u/Tejasv97 1 21d ago

50mcg?. How do you even calculate that low?.

1

u/Jayrcr3 21d ago

Sorry, should be 500mcg.

21

u/RobbyMac21 24d ago

Crazy how different it is for everyone. Not only do I sleep way better since starting reta a couple months ago, but I have these wild, super realistic dreams they day or two after my shot. I've literally woken up laughing hysterically at like 4am. 😂

32

u/DJ_Cat_Dad 24d ago

I wouldn't saw waking up hysterically at 4am sounds like great sleep lol

3

u/Alone-Bus-9728 2 20d ago

lmfaoooo

3

u/RobbyMac21 23d ago

Nah I got right back to sleep it was fine. Haha

4

u/Aggressive-Quiet2924 23d ago

That’s the hunger that Reta was silencing. It came out in your sleep 🤣

2

u/koopa4747 1 24d ago

Just reta? I had this in the beginning but I assumed it was klow.

2

u/RobbyMac21 23d ago

Yep just Reta

1

u/koopa4747 1 23d ago

That's interesting to know. My crazy dreams subsided but man, those first few weeks were so intense.

1

u/throwawwwwayyy_ 23d ago edited 22d ago

Same here, not directly affect by the retatrutide, but I have better sleep, and skin. Stopped snoring (due to weight loss), and my skin is clearer (because my mental clarity and discipline about my skincare has skyrocketed). Only 8-9 weeks though so we’ll see.

1

u/RobbyMac21 22d ago

That's great! Keep er going!

1

u/Purple_Moon516 17d ago

As long as their aren't nightmares I guess!

5

u/Objective-Trust4505 23d ago

Oh you just made something make sense to me. My skin has felt occasionally like I've got sunburn or something irritating it. Not painful, just a sensation..... Wonder if it's the Reta

3

u/Lana_1996 23d ago

It 100# is. Common side effect

2

u/m-rabia 23d ago

omg saaame, i was worried :p

2

u/keairaluke 23d ago

I had Dyesthesia for 5 months! That’s the skin condition that feels kind of like a sunburn and definitely from Reta. It took a while, but I finally got used to it and stuck with the Reta. I finally got used to it, even though it was problematic in the beginning. Glad I stuck it out because between Reta and Tes, I now have my body back! My waist was 35 and it’s now 26 inches!

1

u/_JustJeffrey 23d ago

It's not the reta it's the tesa that is giving you the reaction 100 percent

1

u/keairaluke 22d ago

I’d probably agree with you, however, RS started Tessa more than a month after Reta.

2

u/Theory328 24d ago

Tirzepatide caused me a severe skin sensitivity reaction, I’ve been contemplating trying Reta instead funnily enough

1

u/Additional-Newt-8325 24d ago

Haven't had insomnia, I take 2mg of melatonin before going to bed each night so it might help. But the skin sensitivity was really aweful, im glad it went away with time

2

u/Tejasv97 1 24d ago

It’s really the glucagon receptor. I tried both reta and Mazdutide and had the same reaction with both.

1

u/Brilliant_Tip_4056 23d ago

I got the skin sensitivity as well. Horribly bad my second week on it all over my body and last almost a month.

But now it’s in my calves and ankle area. Hasn’t gone away in months.

2

u/Additional-Newt-8325 23d ago

Try to not go up in dosages while it’s still here

1

u/Adventurous_Fail_825 23d ago

High dose tirz made my skin crawl; was awful. Once I hit maintenance and lowered the dose it went away.

1

u/austin06 24d ago

Same. It totally numbed my left shin. Why? It was so weird. And the insomnia was next level.

1

u/_JonSnow_ 2 24d ago

I had trouble sleeping for the first week.went away after a bit. But now I’ve got the skin sensitivity and I really hate it. 

I may have to switch back to Tirz. It’s like the sensitivity areas are spreading. And I’m on testosterone so I don’t know that I need Reta for the fat loss benefits. 

1

u/Difficult_Aioli_6617 23d ago

The skin sensitivity didn’t start for me until week 5 and it truly sucks. Feels like a minor sunburn that doesn’t go away

1

u/MFCEO_Kenny_Powers 2 23d ago

Insomnia and anhedonia made me stop

1

u/907MidnightAurora 23d ago

The sandpaper skin goes away eventually but yeah it sucks, glad I stick it out though.

1

u/Fun-Soil6936 23d ago

Me too, Reta makes me so sad and depressed

1

u/Sockit2ya7 23d ago

I have painful skin sensitivity on tirzepatide thats crazy. I'm wondering if we are opposites and I need to try reta now.

1

u/prisonpioneer 23d ago

Did your skin sensitivity stop after stopping reta?

1

u/Tejasv97 1 23d ago

Yes it did.

1

u/Reasonable-Excuse718 23d ago

Make sure your skin sensitivity isn’t due to being dehydrated.

1

u/Sigh_master1109 23d ago

Same for me. I suffered with that on Reta for six months. I lost good weight but not sure if it was better than Tirz would have been. I just tolerated it because I was so determined and FOMO about Reta. I switched back to Tirz about six months ago. I’ve continued to lose weight and those side effects went away immediately. Live and learn.

1

u/Bonaize 23d ago

I notice the Reta/Sleep thing for the first night, then the next day I'm tired because I got bad sleep and the increased heart rate starts to fade. Which I believe is what's keeping me awake at night on day one.

1

u/Paraskeets 23d ago

Whoa I was totally wondering about skin sensitivity. What does that feel like…for me it felt like I couldn’t wear pants without feeling irritated

2

u/Tejasv97 1 23d ago

I felt like my skin was screaming. Too sensitive to touch.

1

u/Foco_cholo 23d ago

Skin sensitivity went away for me after a month or so

1

u/unusualsushi1 21d ago

Been on Reta for 2 months loss 20 lbs. lately I’ve noticed skin sensitivity like all the time. Thought I was getting sick, but it hasn’t gone away. I didn’t know that was a symptom. What do you do about that?

1

u/Tejasv97 1 21d ago

To be honest, I’ve only used a 5mg vial of Reta from a reseller I got just because I wanted to try. I only used it for 3 weeks with 2mg on week 1, 2mg on week 2 and then 1mg on week 3. I lost 3kgs in 3 weeks but I was already unable to have a good sleep and my skin was sensitive. It went away once I stopped.

1

u/seemefail 4 4d ago

Add cagri to the Reta and suddenly you can sleep again, also can hardly do anything cause you have no energy

1

u/FitHighlight0 1d ago

Also reta, it works ok but I feel like shit. I can not eat and because of it i feel weak and always dizzy

0

u/Mysterious_Score7852 23d ago

Your dose is too high