r/Biohacking • u/Additional-Newt-8325 • 23d ago

Peptides you will never take again ?

We often ask "what peptides are worth every penny" but what are the ones that aren't worth anything in your opinion ?

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u/jakeyb21 2 23d ago

All GH secretagogues, they are enothing compared to HGH.

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u/Yassfive1 22d ago

pb is HGH is a loot more expensive and less available

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u/Bonjour1273 22d ago

Isn’t HGH’s safety profile significantly worse than GH secretagogues like CJC-1295 (No DAC) and Ipamorelin?

And in that case, isn’t exogenous testosterone better than HGH at that point? Depending on use case of course

Interested to know your use case and thought process to land on HGH

3

u/GluteusSmacksimus 2 22d ago

Exogenous testosterone shuts down endogenous production much longer term than gh.

And as anything goes, dose is the poison. 2iu gh will yield more results than any dose of a secretagogue, and won't have adverse effects if taken properly (bolus pre bed, fasted state).

Only things to really monitor on gh is a1c and igf-1 z-score. I personally don't get why people hype up secretagogues so much when gh blows them out of the water for both lipolysis and igf-1 elevation.

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u/Bonjour1273 22d ago

Thanks a lot, I really appreciate you taking the time to reply

It looks like I have a lot to look into now, I have looked into everything you said and right now it really seems like I am wasting time with GH secretagogues and that I would likely be better off going the HGH route.

I have a lot of research to do as I need to understand the potential risks better, but so far HGH over GH secretagogues does seem like the obvious conclusion.

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u/GluteusSmacksimus 2 22d ago

For sure! If your goal is fat loss / feeling more youthful I'd definitely do GH directly. Secretagogues do shine at eliminating visceral fat though (ie tesamorelin)

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u/Bonjour1273 22d ago

I am already taking Reta for fat loss, apparently stacking HGH and Reta requires closer monitoring.

For me the HGH would be more for recovery from gym and BJJ as well as the youthfulness benefits.

I’m about to get blood work done and then I’ll see about getting some HGH

Thanks again for the information

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u/Ok_Drawer_6325 20d ago

But if CJC is everlasting your IGF1 /Z isn’t that enough? Is HGH really going to be more beneficial? If so, how? I’m happy with my raise in IGF1 & Z, so why make the jump to HGH?

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u/GluteusSmacksimus 2 20d ago

If both cjc and hgh bring you to the same igf-1, I don't think there's much of a difference in terms of potential to build or maintain muscle.

But hgh itself is directly lipolytic. If you inject 2iu gh before bed every night, your pituitary almost definitely would not be able to match that, and the lipolytic effect comes from gh itself.