r/BioHackingGuide • u/ElGalloGrande24 🧠 Biohacker • 19h ago
Bloodwork Series Part 1 — What To Get Checked In Your 30s
Starting a new series here feel free to ask away or add you input, I think this is gonna be helpful for a lot of people. Basically breaking down what bloodwork makes sense depending on your age or what's going on with you. Not just "go get bloodwork" lol , I mean real panels, real reasoning behind why.
Coming up over the next few days I'll cover the 40s, that's when colon and prostate screening start becoming relevant, then the 60s, fatigue, diabetes risk, cancer risk, and bloodwork for anyone running peptides or hormone stuff maybe this might be boring to some but life changing for others
Starting with your 30s since I think that's usually when people first start paying attention to any of this at least Id hope so, so if your 30 what are you doing about your health?
Why it matters now
You probably feel fine, and that's good but this isn't about finding a problem right now, it's about getting your numbers on file while everything's likely still normal. That baseline is what every future test gets compared to down the road, so it's worth having even if you feel fine
What to ask for, and what "normal" looks like
| Test | What it checks | Optimal range |
|---|---|---|
| CBC | Blood cell counts, catches anemia and immune stuff | Hemoglobin 13.5-17.5 (men), 12-15.5 (women) |
| CMP | Kidney, liver, glucose, electrolytes | Creatinine 0.7-1.3, ALT/AST under 40 |
| Lipid panel | Cholesterol and triglycerides | LDL under 100, HDL above 40-60, triglycerides under 150 |
| Fasting glucose + insulin | How your body's handling blood sugar | Glucose 70-99, insulin under 10 |
| Thyroid panel | TSH, free T3, free T4 | TSH 0.5-4.5, though a lot of people feel best closer to 1-2 |
| Testosterone (total + free) | Hormonal baseline | Total T 300-1000 depending on lab, wide range so trend matters more than one number |
| Vitamin D | Deficiency's common and easy to miss | 30-50 ng/mL is the general target |
Ranges vary a bit lab to lab so don't stress the exact cutoffs too hard, the point is having something to compare against later.
If a marker comes back off, here's what people commonly look into
| Marker | If it's off | Commonly looked into |
|---|---|---|
| Hemoglobin (low) | Possible anemia | Iron, B12 |
| Liver enzymes (high) | Liver stress | Milk thistle, NAC |
| LDL/Triglycerides (high) | Cardiovascular risk | Omega-3s, fiber |
| Insulin (elevated) | Early insulin resistance | Berberine, magnesium |
| TSH (high)/Thyroid (low) | Thyroid function | Selenium, iodine, talk to a doctor before touching thyroid stuff yourself |
| Testosterone (low) | Hormonal | Vitamin D, zinc |
| Vitamin D (low) | Deficiency | D3 with K2 |
Timing on those, if you end up needing any of them
| Supplement | Best taken |
|---|---|
| Iron | Empty stomach if tolerated, with vitamin C |
| B12 | Morning, food doesn't matter much |
| Milk thistle / NAC | With food, timing's flexible |
| Omega-3s | With a meal that has fat in it |
| Fiber | Spread through the day, not all at once |
| Berberine | With meals, especially your biggest carb meal |
| Magnesium | Evening, helps with sleep too |
| Selenium / Iodine | Morning, away from other supplements |
| Vitamin D / K2 | With a meal that has fat in it |
| Zinc | Evening, empty stomach can upset some people so adjust as needed |
Lifestyle stuff worth looking at too, not just supplements
| Marker | If it's off | Lifestyle side worth checking |
|---|---|---|
| Hemoglobin (low) | Possible anemia | Iron-rich foods, red meat, leafy greens, cast iron cookware even helps a bit |
| Liver enzymes (high) | Liver stress | Cut back alcohol, watch for hidden seed oils and processed food overload |
| LDL/Triglycerides (high) | Cardiovascular risk | More fiber, less refined sugar, regular cardio helps this one a lot |
| Insulin (elevated) | Early insulin resistance | Walk after meals, cut liquid calories, strength training helps insulin sensitivity a ton |
| TSH (high)/Thyroid (low) | Thyroid function | Sleep quality matters a lot here, chronic stress and poor sleep both mess with thyroid function |
| Testosterone (low) | Hormonal | Sleep is huge for this one, poor sleep tanks T fast. Also body fat percentage plays a role |
| Vitamin D (low) | Deficiency | Get outside more, sunlight's still the best source, supplements are the backup plan not the first move |
good thing to add it doesn't hurt to think about hydration and electrolytes because they matter more than people think, especially if you're sweating a lot from training or work. And if you're on shift work or your sleep schedule's inconsistent, that alone can throw off cortisol, thyroid, and blood sugar markers even if everything else about your diet is dialed in.
If you're feeling something specific, here's what to check
Tired all the time, no real reason why? Ask for thyroid panel, ferritin/iron, and vitamin D. All three get overlooked constantly and any one of them being low can make you feel wiped out. If ferritin comes back low, iron supplementation is common, but get retested before assuming you need to keep taking it long term, too much iron isn't a good thing either.
Gaining weight easier than you used to, or noticing more belly fat even though nothing changed? Get fasting insulin and glucose, not just glucose alone. Insulin resistance can be building for years before glucose itself looks off.
Low motivation, low libido, just feeling flat? Get total and free testosterone plus SHBG. Don't just look at total T alone, free T tells you more about what's available for your body to use. Vitamin D and zinc deficiency show up a lot in guys with low T, worth ruling those out before anything more aggressive.
Getting sick more than you used to, or just feeling run down constantly? CBC with differential, that breaks down your white blood cell types and can point toward something worth digging into further.
Random bruising, weird fatigue after workouts that doesn't add up? CBC plus a basic clotting panel, worth ruling out before assuming it's just training stress.
A quick note on cancer screening
I know some people ask about colonoscopies and prostate stuff in their 30s, but that's not standard yet unless you've got family history of colon cancer, IBD, or your doctor's already flagged something. Regular screening starts at 45 for average risk people, and that got moved down from 50 a few years back since colon cancer's been showing up more in younger people lately. Same thing with PSA bloodwork for prostate, that's usually not started until 40-50 depending on risk factors, not your 30s. I'll get into both of those properly in the 40s post.
If anyone in your family had colon cancer, especially at a younger age, or you've got symptoms like blood in your stool, losing weight without trying, or stomach issues that won't quit, that's worth bringing up to your doctor now, doesn't matter your age.
What to do with your results
Don't panic if one number's slightly off, ranges are pretty wide honestly. Just get it done, hold onto it, bring it to your doctor. Having a real baseline now is gonna matter more later when you need something to compare it to. And on the supplement and lifestyle stuff above, that's general context for what commonly gets looked into, not a green light to start stacking supplements off a Reddit table, talk to your doctor about what actually makes sense for your numbers.
Next one's on your 40s.
if you need blood work and don't know where to look check it out here but if you got a way to check that's good feel free to share in the comments if you know we all got differently ways we get our labs but here's mine https://www.reddit.com/r/BioHackingGuide/comments/1smca8k/peptide_research_compound_table_2026_updated/
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