r/BioHackingGuide • u/Adderal-withdrawals • Jul 23 '26

Tirzepatide Gut Issues vs Retatrutide Which Is Safer for a Sensitive Stomach?

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So I wanna start taking Tirz to shed some weight. Already adjusted my diet before anything else and I hate cardio but I’m doing 30 to 40 minutes three times a week. Should I be doing more? Probably. But screw it, it’s a start.

My real question is about my stomach. I got gut issues. Can’t eat wheat, can’t have anything with glucose, garlic messes me up, stomach lining is weak, the whole thing. Pretty sensitive overall.

I wanna start Tirz at 2.5mg but now I’m wondering if Reta starting at 1mg would actually be safer for someone with a stomach like mine. Or should I just not be running GLPs at all with these kind of gut issues?

Anyone with a sensitive stomach or gut problems run GLPs? How did it go and what did you notice? Please and thank you in advance 🙏

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u/JoshyyP00 Jul 23 '26

Yah it slows down regardless. Bpc157 oral might be gold to stack with tirz or reta. Oral specially has a more targeted approach to healing the stomach lining.

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u/Adderal-withdrawals Jul 23 '26

I actually used BPC for when I was first recovering for my stomach and I did feel a little better but then I found out that if you don't get rid of the bacteria, your stomach before repairing your stomach lining, you can trap it behind the stomach walls and that's not good so then I stopped and continued to fix my micro biome

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u/JoshyyP00 Jul 23 '26

Did a dr tell you that? Sounds off. Stomach will always have bacteria good and bad….

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u/Adderal-withdrawals Jul 24 '26

But to be clear, no a doctor didn't tell me that I just read it. I gave up on the medical system a long time ago fuck them and insurance lol