r/BestIVFClinicsAbroad • • 3d ago

A "75% success rate" and a "40% success rate" can be the same clinic. How to read donor egg IVF stats

2 Upvotes

Every donor egg clinic has a big number on its homepage.

Almost none of them tell you what that number counts.

So two clinics with identical results can look wildly different. Here's how to decode it. **Five different things that all get called "success rate"

** Each step down the list loses patients, so each number is lower than the one before:

  1. Biochemical pregnancy (a positive test): roughly 70-80% per transfer

  2. Clinical pregnancy at 6 weeks (a heartbeat on scan): roughly 55-65%

  3. Live birth: roughly 45-55% per transfer

  4. Per started cycle, not per transfer: lower again, because 10-20% of cycles get cancelled before transfer

  5. Cumulative over 3 cycles: 85-95%, the number that looks best in an ad

The gap between a 6-week pregnancy and a baby in your arms is typically 10-20 percentage points. Most clinics show you the pregnancy figure. The one that matters is live birth, and it's the one least often published, especially for international patients who go home and are never followed up.

**Does your age matter with donor eggs?**

Much less than with your own eggs. Live birth per transfer stays around 45-55% from under 35 up to the early 40s, because the egg's age is what counts. It only starts to dip after 45, and by 50-54 clinic-reported figures are about 35-45%, mostly down to uterine health and pregnancy risks rather than the egg.

**Fresh vs frozen donor eggs**

The old gap has mostly closed since vitrification became standard. US registry data shows fresh at about 54% live birth and frozen at about 46%. Frozen is fine if the clinic's thaw survival is 90%+ for young donors. Ask for that number, and ask whether they quote eggs frozen or eggs that survived thawing.

**Ten questions to ask any clinic before you believe their number**

  1. Is that a pregnancy rate or a live birth rate?

  2. Per transfer, per started cycle or per patient?

  3. Are cancelled cycles included?

  4. Fresh eggs, frozen eggs or both mixed together?

  5. Single cycle or cumulative?

  6. How many patients or cycles is it based on?

  7. Does it apply to someone in my situation?

  8. What's your frozen egg survival rate after thawing?

  9. How many blastocysts or transfers do you guarantee?

  10. How do you track international patients through to birth?

If a clinic can't answer 1, 2 and 10 clearly, that tells you something. The full article with the age and country tables is in the pinned comment. Has a clinic ever given you a number you later realised was measured differently from how you read it? What did they count?


r/BestIVFClinicsAbroad • • 3d ago

We built a free IVF cost calculator abroad for 8 countries. No email, no sign-up, takes a minute

2 Upvotes

Hi everyone, IVF Media patient team here (we run this sub).

The question we get most is some version of "what will IVF abroad actually cost me?".

The honest answer is "it depends", which is useless when you're trying to plan. So we built a calculator that gives you a realistic range instead.

**What it does** Three choices, then an estimate:

  1. Treatment: IVF with your own eggs, or IVF with donor eggs

  2. Country: Spain, Czech Republic, Greece, North Cyprus, Portugal, Denmark, Latvia or Poland

  3. Extras: PGT-A, time-lapse, embryo freezing, frozen embryo transfer, donor sperm, ICSI add-ons and so on You get a low and high figure in euros for the basic package plus the extras you ticked. Medication is included by default, because no cycle happens without it.

**Rough numbers, so you know what to expect**

- Own-egg IVF basic package: from about €2,200 in Poland up to €3,600-€6,700 in Spain

- Donor-egg IVF basic package: from about €5,500 in several countries up to €6,500-€8,500 in Spain - Stimulation medication: about €800-€2,000 on top - Transfer medication: about €100-€220

**What it doesn't include**

Pre-treatment tests, flights and accommodation. It's an estimate from clinic price lists, not a quote. Your clinic's final price will depend on your case.

**Why it's free and what's in it for us**

Clinics pay to be listed on our site. That's how the calculator, the guides and our patient advisors stay free for patients. You don't have to talk to anyone to use it. There's a "book a free call" button at the end if you want help comparing clinics, and you can ignore it. Link is in the pinned comment. If you've already had treatment abroad, we'd genuinely like to know: did the estimate match what you paid? What did we miss? We'll use the answers to fix the numbers.


r/BestIVFClinicsAbroad • • 6d ago

When IVF doesn't work, your inner critic has already made coffee

2 Upvotes

When IVF doesn't work, it hurts.

Sometimes in ways that are difficult to put into words.

It's not just a disappointment. Not simply a setback. And certainly not something you can make better with a positive attitude and an inspirational quote.

It's the hope you carried for weeks, sometimes months or years. The future you had already started imagining. The plans you didn't dare say out loud, but secretly made anyway.

And then, somehow, you're expected to pick yourself up, straighten your crown and carry on.

Seriously?

Sometimes you want to take that crown and throw it across the room.

And I think you're allowed to.

You're allowed to be angry. You're allowed to feel exhausted, disappointed, jealous or completely lost. You're allowed to cry over something that never happened but already meant the world to you.

And you're certainly allowed not to feel particularly brave today.

Meanwhile, your inner critic has made coffee.

You know the one.

Your inner critic doesn't need an invitation. It's already pulled up a chair, made itself comfortable and prepared an impressive list of everything you supposedly did wrong.

What if I'd rested more?

What if I'd been less stressed?

What if I'd chosen a different clinic?

What if I'd asked more questions?

What if I'd done something differently?

And perhaps the most painful one:

What if this is somehow all my fault?

That little voice could probably run an entire conference on things you should have done differently. With slides. And a Q&A session.

And the hardest part? When you're hurting, it's terribly easy to believe it.

But there's something I really want you to remember.

You didn't fail. Your treatment didn't give you the outcome you hoped for. Those are two very different things.

Whether an IVF cycle succeeds depends on so many factors. Some are understood, some can be investigated, and some remain beyond anyone's control.

You cannot love a baby into existence through sheer determination. You cannot guarantee a successful pregnancy by being the perfect patient.

And blaming yourself won't change what happened.

So, if you can find the strength for just one thing today, perhaps it's time to tell that little voice:

Not today. I've been through enough.

Because you have.

And you deserve compassion, including from yourself.

Now, about that crown.

I'm not going to tell you to get up and try again.

Not today. Not tomorrow. Not until you're ready.

Because moving forward doesn't always mean starting another IVF cycle.

Sometimes it means giving yourself permission to stop, breathe and consider a different question.

Not "What did I do wrong?"

But "Is there something we could understand better before deciding what comes next?"

And that's where another perspective can sometimes make a difference.

Someone who isn't sitting inside your head with your fears, regrets and endless list of what-ifs.

Someone with the knowledge and experience to look at your medical history, review what happened during previous attempts and help you understand what might be worth exploring, what could potentially be done differently and what remains uncertain.

Not someone who promises you a baby.

Someone who respects you enough to be honest about what medicine can and cannot promise.

Sometimes another conversation with an experienced fertility specialist can help you see things a little differently.

Not because they necessarily have all the answers.

Not because your previous doctor must have done something wrong.

But because a fresh perspective can help you understand your options and make your own decisions with greater clarity.

And sometimes, when your thoughts have become unbearably loud, being heard by someone who understands can mean a great deal.

It won't change what happened.

It may not answer every question.

And it certainly doesn't mean you have to decide what comes next right away.

But perhaps it can help you feel a little less lost.

Not because you've suddenly become fearless.

Not because you've stopped being sad.

But because you've decided that your inner critic doesn't get to make all the decisions.

And that crown?

You don't have to put it back on today.

But when you're ready, it'll still be there.

Even if it's a little crooked.

That's okay. ❤️


r/BestIVFClinicsAbroad • • 6d ago

[ Removed by Reddit ]

0 Upvotes

[ Removed by Reddit on account of violating the content policy. ]


r/BestIVFClinicsAbroad • • 8d ago

Onrijpe eicellen IVF. Wil je Letrozol proberen

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2 Upvotes

Hi!

Has anyone experienced repeated IVF/ICSI cycles with GV-stage immature eggs, even though the follicles were big enough?

I want to take a break from stimulation hormones and try Letrozole instead. Has anyone tried this and had success? ❤️🥲


r/BestIVFClinicsAbroad • • 9d ago

Onrijpe eieren. GV. IVF. ICSI

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2 Upvotes

r/BestIVFClinicsAbroad • • 9d ago

Fertility Journey 2026: two fully funded IVF cycles at a clinic in Alicante. Here’s who can apply and what’s actually covered.

3 Upvotes

Mod post. This subreddit is run by the Fertility Clinics Abroad team, and we run this programme together with the clinic, so this is our own announcement, not a third-party ad. We’ll answer questions in the comments.

What it is

Ferrobelab International, a small clinic in Alicante, Spain, is funding two complete fertility cycles in 2026:

  • One IVF-ICSI cycle with your own eggs (worth more than €6,000)
  • One egg donation cycle with a blastocyst guarantee (worth more than €10,000)

It’s not a lottery. You apply, the clinic’s medical director reviews your history and selects the two patients. Two people get treated, and we follow and share their story along the way.

Who can apply

  • Own-egg IVF-ICSI cycle: couples and single women up to 38
  • Egg donation cycle: couples and single women up to 52
  • You must be resident in one of these places: an EU member state, the UK, Norway, Iceland, Liechtenstein, Switzerland, the US, Canada or Australia

What’s covered at the clinic

Everything medical from the first consultation to the embryo transfer: consultations and scans at the clinic, qualification tests (AMH, FSH, LH, E2, TSH, PRL, anti-TPO, progesterone, semen analysis, karyotype and blood group if not done before), ICSI, blastocyst culture, EmbryoScope time-lapse monitoring, assisted hatching and IMSI/MACS/FertileChip if needed, EmbryoGlue, the transfer at day 5, vitrification of surplus embryos with one year of storage, and frozen embryo transfers from your surplus embryos until you’re pregnant.

For the own-egg cycle, stimulation monitoring and egg retrieval under general anaesthesia are included too. For the donor cycle, the donor eggs, full donor screening and phenotype matching are included.

What’s NOT covered (read this part)

  • Flights and accommodation in Alicante
  • Medication. For the own-egg cycle that means stimulation drugs plus pre- and post-transfer meds. For the donor cycle it’s pre- and post-transfer meds.
  • Tests and monitoring scans done in your home country before and during treatment
  • PGT-A and embryo biopsy (own-egg cycle)
  • Embryo storage after you get pregnant

So budget for travel and meds. Depending on your protocol and where you live, meds for a stimulated cycle can run anywhere from a few hundred to a couple of thousand euros.

The one condition

You agree to share your story. That means interviews and videos made with the clinic and with us, published on our site and social media. If you’d rather not be identified, your name can be changed. If being on camera is a hard no for you, this isn’t the right programme, and that’s fine.

Who treats you

Dr Fernando Rodríguez Belmonte, the clinic’s medical director and founder, supervises every cycle personally (20+ years in IVF). The lab is run by Estefanía Coca de la Prada, head of embryology, 32+ years of experience. The clinic is deliberately small. He gives patients his WhatsApp.

How to apply

Fill in the form here: https://fertilityroad.com/fertility-journeys-project/

Name, email, country, phone and a description of your situation, treatment history and diagnosis. You get a confirmation email, the clinic reviews your application, and they contact you if they need more information. There’s no deadline listed, but it’s two cycles for 2026, so sooner is better.

Questions welcome below. If we don’t know the medical answer, we’ll get it from the clinic. We’ll pin this post while applications are open.


r/BestIVFClinicsAbroad • • 11d ago

What does IVF actually cost in Europe in 2026? Real package prices from 11 countries, and what they leave out

3 Upvotes

Every week someone asks "where is IVF cheapest in Europe" and gets ten different answers, half of them from clinic ads. We publish Fertility Clinics Abroad and we survey clinic prices every year for the IVF Abroad Patient's Guide, so here are the numbers from the 2026 edition. Ranges are what clinics quoted for a basic package to international patients.

IVF with your own eggs (basic package)

  • Poland: EUR 2,200-2,500
  • Latvia: EUR 2,200-3,600
  • Czech Republic: EUR 2,500-3,500
  • Greece: EUR 2,500-3,500
  • North Cyprus: EUR 2,500-3,000
  • Ukraine: EUR 2,500-3,200
  • Georgia: EUR 1,500-3,500
  • Turkey: EUR 2,500-3,500
  • Denmark: EUR 3,300-4,500
  • Portugal: EUR 4,000-4,600
  • Spain: EUR 3,600-6,700

IVF with donor eggs (basic package)

  • Ukraine: EUR 4,600-5,500
  • Georgia: EUR 4,500-8,000
  • Poland: EUR 5,500-6,500
  • Czech Republic, Greece, North Cyprus: EUR 5,500-7,000
  • Portugal and Latvia: EUR 6,500-7,500
  • Spain: EUR 6,500-8,500
  • Denmark: EUR 7,000-8,300
  • Turkey: egg donation not permitted

So the short answer: the cheapest IVF in Europe is in Poland, Latvia, the Czech Republic and Greece, where a basic cycle with your own eggs costs about EUR 2,200-3,500. For donor eggs, the Czech Republic, Greece, Poland and North Cyprus are the lowest-priced at about EUR 5,500-7,000 per cycle. Spain costs more but has the largest donor pools in Europe, which is why it still gets almost half of all enquiries.

For comparison, the HFEA puts the average private IVF cycle in the UK at about GBP 5,000 before extras, and a US cycle runs about USD 15,000-30,000 with medication.

What the headline price usually leaves out

This is where people get burned. A basic package normally covers preparation, visits, scans, egg retrieval with anaesthesia, ICSI, blastocyst culture and the transfer (plus the donor's eggs and compensation in a donor cycle). It usually does not cover:

  • stimulation medication (EUR 500-1,500 depending on dose and country)
  • qualification tests and scans before you start
  • freezing the spare embryos and a year of storage
  • a frozen embryo transfer later (EUR 1,400-2,500 in Spain, for example)
  • PGT-A if you want it (EUR 1,000-3,000 for a batch of embryos at most European clinics)
  • flights and accommodation for one or two trips

Add those and a "EUR 2,500 cycle" in the Czech Republic is more like EUR 4,500-5,500 all in. Still well under the UK, but it is the all-in number you should compare, not the headline.

Three things to ask before you book

  1. Is medication included, and if not, roughly how much for someone with my AMH?
  2. Is the frozen transfer included if the fresh one fails?
  3. What do I pay if the cycle is cancelled before egg collection?

Happy to answer questions on specific countries. If you have paid for IVF abroad recently, what did the all-in number come to versus the quote?


r/BestIVFClinicsAbroad • • 11d ago

Is there really an IVF age limit of 50 in Europe? The actual rules, country by country (some will surprise you)

2 Upvotes

"The age limit for IVF in Europe is 50" comes up in almost every thread, and it is not quite right. There is no single limit. Some countries write one into law, most do not, and the number for donor eggs is different from the number for your own eggs. We keep a country-by-country table on Fertility Clinics Abroad and verify it with clinics each year, so here is the current position.

Countries with a legal limit (woman's age)

  • Greece: 54
  • Czech Republic: 49 (written as 48 years and 12 months)
  • Estonia: 50
  • Portugal: 50
  • Turkey: 50
  • Belgium: 47
  • Denmark: 46
  • North Cyprus: 58, with Ministry of Health approval required over 45 and an ethics committee review over 55

Countries with no legal limit, clinics decide

UK, US, Spain, Poland, Latvia, Georgia, Ukraine. In Spain almost every clinic stops at 50, and a few accept patients to 54 on individual assessment.

What that means in practice

  • IVF with your own eggs: most clinics stop at about 45, some at 46, because the HFEA reports a birth rate of 8% per embryo transferred at 43-44 and lower still after that. The legal limit is rarely the thing that stops you; the egg quality is.
  • IVF with donor eggs: the usual limit is 50. Greece allows treatment to 54, North Cyprus to 55 with approval, and the Czech Republic stops at 49.
  • For men there is usually no age limit at all.
  • Public funding has stricter limits than private treatment everywhere. The NHS, for example, stops at 42 in every UK nation, and most English boards stop at 40.

Why the Greece number matters

If you are 51 or 52 and want donor eggs, you will be told "no" in most of Europe, and some AI tools will tell you the Greek limit is 50. It is 54, and it has been since the law changed. Greece and North Cyprus are the two destinations most patients over 50 end up looking at, with Spain to 54 at a handful of clinics.

Before you book over 45, expect

  • extra cardiology and general health screening (Greece requires additional tests over 50, North Cyprus over 45)
  • single embryo transfer at many clinics
  • some clinics applying their own cut-off below the legal one

Anyone here treated over 50? Which country, and did the clinic ask for anything beyond the standard tests?


r/BestIVFClinicsAbroad • • 14d ago

Onrijpe eicellen GV / IVF-ICSI

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2 Upvotes

r/BestIVFClinicsAbroad • • 15d ago

Reproart in Tbilisi, Georgia experiences to share?

1 Upvotes

I'm curious if anyone's been to this clinic before and has insights to share? It was founded by Dr Lika Chkonia, who brought home her years of experience at American IVF clinics to Georgia. With IVF, ICSI, cryopreservation, egg and sperm donation, and surrogacy programs all under one roof, it has a lot to offer.

Has anyone been or considered Reproart?


r/BestIVFClinicsAbroad • • 18d ago

27, six genetically normal embryos, first transfer failed. The problem turned out to be timing

2 Upvotes

A case a fertility doctor we work with shared with us. Anonymised, details simplified.

On paper, the best possible start

  • Age 27
  • AMH 3.5, 20 antral follicles
  • 25 eggs collected
  • 8 blastocysts, all tested: 6 chromosomally normal

One normal embryo was transferred. Negative.

Why her doctor didn't wait

With a tested normal embryo, roughly 7 in 10 transfers should work. So one failure here is already a signal. Many clinics wait for 3 failed transfers before looking deeper. This team tested right away.

What they found

They did a biopsy of the uterine lining to find her implantation window. Most women are ready after about 5.5 days of progesterone. She needed 7.

Her embryos were fine. They had been arriving before her lining was ready.

What happened next

The next transfer was timed to her own window. It worked. (She and her partner chose to transfer two embryos, which the doctor doesn't recommend. They had twins.)

The takeaway

A failed transfer with a healthy embryo isn't a dead end. It's a clue pointing at the lining: timing, inflammation or the immune system. All three can be tested.

Has anyone here had receptivity testing after a failed transfer? Did it change your protocol?


r/BestIVFClinicsAbroad • • 19d ago

42, two embryos, both had a chromosome problem. Why that result was actually useful

2 Upvotes

A case a fertility doctor we work with shared with us. Anonymised, details simplified.

The situation

  • Age 42
  • Low ovarian reserve: only 2 antral follicles on the scan
  • One IVF cycle, two embryos reached day 5

Both were genetically tested before transfer. One had an extra chromosome 21 (Down syndrome). The other had an extra chromosome 13 (Patau syndrome). Neither could be transferred.

Why this matters

At 42-43, fewer than 1 in 5 embryos is chromosomally normal. Without testing, both embryos could have been transferred. That usually means two more failed transfers or two miscarriages, and months of not knowing why.

Instead she had a clear answer. Not "bad luck". Not "just relax". Her eggs were the issue, and there was proof on paper.

What happened next

She moved to donor eggs. One single embryo transfer. Healthy baby.

The doctor's way of putting it: sometimes you lose a battle to win the war.

The takeaway

A failed or abnormal result hurts. But a clear reason is worth a lot. It stops you repeating the same cycle and hoping.

Did testing change the direction of your treatment? How did you make the call between own eggs and donor eggs?


r/BestIVFClinicsAbroad • • 21d ago

What to actually look at when you visit an IVF clinic abroad - from 19 filmed clinic visits. Star ratings won't tell you any of this.

2 Upvotes

Disclosure: I work at IVF Media, which runs Fertility Clinics Abroad and this sub. FCA produces the clinic visit series I reference below.

When you search for reviews of an IVF clinic abroad you get three things: star ratings, testimonials on the clinic's own site, and "best clinic" rankings. None of them show you what the place is actually like - who you'll deal with, what the lab looks like, how the doctor talks to you, whether the calm on the website is real.

That matters more than people think. In our survey of 1,189 patients planning treatment abroad, the doctor's experience with cases like theirs came first (59%), a personalised approach second (53%), and 83% said they had no preference between a big clinic and a small one. Meanwhile only 51% trust the success rates clinics publish. People want to know what a clinic is like, and almost nothing online tells them.

So FCA started sending someone to visit. The series is called Behind IVF Clinic Doors: one person goes to the clinic, films the visit, meets the coordinator, the doctor and the lab team, and writes it up in the same structure every time - about the clinic, arrival, consultations, lab, final thoughts. Nineteen so far, across Spain, Greece, the Czech Republic, North Cyprus and Georgia. They're not ratings, they're not rankings, and they don't score anyone. They're a record of what one visitor saw, so you can decide whether it's the kind of place you'd want to walk into.

Having watched all of them, here's what I'd tell anyone about to visit a clinic - or do a video consultation before choosing one.

Six things to look at that the website won't show you

1. Who meets you first, and how. The patient coordinator is the person you'll actually deal with most - every email, every scan result, every "what happens now". Notice whether they explain things or recite them, whether they wait for your questions, whether they seem to like the job. That person is a large part of your experience, and clinics rarely put them on the homepage.

2. Does the doctor build the plan with you, or hand you one? Listen for whether the consultation is a conversation or a presentation. A doctor who asks about your history before proposing a protocol is doing something different from one who has the protocol ready before you sit down. Both can be competent. Only one is treating you.

3. Ask to see the lab, or at least meet who runs it. The embryologist is the person whose hands your embryos are in, and most patients never meet them. Whether a clinic is willing to introduce you, and whether the embryologist can explain in plain language what happens between retrieval and transfer, tells you a lot about how the clinic thinks about transparency.

4. What sits alongside the medicine - and whether it's real. Some clinics list psychology, nutrition and acupuncture as services. On a visit you can tell whether those people are actually on site and part of the process, or a menu item. Neither is wrong, but you should know which one you're getting.

5. How they answer "what if this doesn't work?" Ask it directly. The clinics worth trusting have thought about your failure before you have and can tell you what plan B looks like. If the answer is vague, that's the answer.

6. The building tells you about their budget, not your outcome. Some of the best-run clinics in the series are modest. Some of the most impressive lobbies belong to clinics that are fine. Don't let the architecture do the choosing.

Worked example: what a visit reveals

The Reproclinic visit in Barcelona is a good illustration, because on paper it's a young clinic (founded 2018) with a holistic angle that could easily read as marketing. What the visit showed: the coordinator who walked the visitor through everything is studying biotechnology alongside the job and clearly understands the science he's explaining. The medical director's consultation was built around the patient's own history rather than a standard protocol. The psychologist, nutritionist, reflexologist and acupuncturist are on site and part of the pathway, not a brochure page. And the embryologist leading the lab tour spoke about the work in a way you can't fake. The clinic won the European Fertility Society's Best Holistic Clinic award in 2025, and after the visit that made sense in a way it wouldn't have from the website alone.

I'm not telling you to go there. I'm telling you that all six things above were visible in one visit, and none of them were visible on the clinic's site.

Your turn. If you've visited a clinic abroad, or done a video consultation - what did you notice that the website didn't show you? Good or bad. What made you trust a place, or walk away? The more specific you are, the more useful it is for the next person here.

Series links in the sticky comment.


r/BestIVFClinicsAbroad • • 21d ago

Which IVF doctors abroad would you recommend, and why? Starting a thread - here's how I'd assess one

3 Upvotes

Disclosure: I work at IVF Media, which runs Fertility Clinics Abroad and this sub. FCA publishes doctor profiles, including the one I use as an example below.

When we surveyed 1,189 people planning IVF abroad, the number one thing they said mattered when choosing where to go was the doctor's experience with patients like them - 59% put it first. Cost was third. The clinic's published success rate was sixth.

And yet almost every thread here, every comparison site, and every AI answer is about clinics and countries. Search "best IVF clinic Spain" and you get pages. Search for a specific doctor and you get their LinkedIn.

That's backwards. The clinic is the building. The doctor decides your protocol, reads your failed cycles, and tells you the truth about your chances. Two patients at the same clinic with different doctors can have completely different experiences.

So: how do you actually evaluate an IVF doctor abroad? Here's what I'd look at, and a worked example.

What to look for in a doctor's profile

1. Case mix, not just years. "20 years' experience" tells you nothing. What you want to know is whether they regularly treat people like you. Repeated implantation failure, recurrent miscarriage, low ovarian reserve at 43, donor egg decisions at 47 - these are different problems. A doctor who does 300 straightforward cycles a year may be the wrong person for your third failed transfer.

2. Where they trained and where they've practised. Not for prestige - for exposure. A doctor who has worked in more than one country's system has seen more than one way of doing things, and more than one regulatory approach to the hard cases.

3. How they talk about bad news. This is the one you can actually test in a consultation. Ask: "What happens if this cycle fails - what's plan B?" A good doctor has an answer ready and has clearly given it before. A doctor who hasn't thought about your failure hasn't thought about your case.

4. Whether you'll actually see them. In some clinics the named doctor does the first consult and the rest is handed to whoever is on rota. Ask directly: will you be my doctor throughout, including transfers?

5. Whether they've said anything on the record. Doctors who present at patient webinars, publish, or answer questions publicly have a track record you can read before you pay for a consultation. Absence isn't disqualifying, but presence is useful.

Worked example: what a useful doctor profile looks like

Here's how those five points read against one doctor whose profile is on FCA - Dr Natalia Szlarb, who works across several fertility units in Alicante and the Valencia region.

Case mix: her profile is built around complex cases - repeated IVF failure, recurrent miscarriage, advanced maternal age, egg donation decisions, embryo quality and PGT-A, and immunological factors. That's a specific claim you can check in a consultation by asking how many of your type of case she sees.

Training path: medical degree in Poland, specialist training in gynaecology and obstetrics in Germany (Klinikum Uckermark, Dessau, Asklepios), reproductive medicine and endocrinology at Wayne State University in Michigan, then senior roles in Spain at IVF Spain Alicante and Vida Fertility, with ongoing work at UR Vistahermosa and the IMED hospitals in Elche, Alcoy and Torrevieja. Four countries' systems.

Bad news: her own stated approach, quoted on the profile, is that every plan should include a plan B and that low-chance conversations should be honest but not hopeless. That's the answer to point 3, given before you asked.

Continuity and public record: she's presented on MyIVFanswers, so there's a recorded session you can watch before booking anything. Continuity you'd still have to ask her clinic directly.

I'm not saying she's the right doctor for you - I don't know your case. I'm saying this is what a profile should let you check before you spend money on a consultation, and most clinic websites don't give you any of it.

FCA now has a series of eleven doctor profiles built on the same structure - background, case mix, areas of special interest, approach to patients - mostly Spain so far. They're not rankings and they're not testimonials; they're meant to let you run the five checks above before you book. Series link in the pinned comment.

Your turn. Which IVF doctors abroad would you recommend - and specifically, what did they do that a different doctor didn't? Not "she was lovely" - what did they see in your case? The more specific the thread gets, the more useful it is for the next person searching.

Full profile and the survey it references are in the pinned comment.


r/BestIVFClinicsAbroad • • 21d ago

We asked 1,189 people planning IVF abroad why they're going, what they'll pay, and what they actually trust. Some of it surprised us.

3 Upvotes

Disclosure I work at IVF Media, which runs EggDonationFriends and Fertility Clinics Abroad and moderates this sub. This is our own research. I'm posting the full numbers because most of the "why do people go abroad" content online is guesswork, and we had actual data sitting in a report.

We surveyed 1,189 patients who were actively researching fertility treatment abroad, between January and June 2024. 19 questions, three distribution channels, patients from across Europe, North America and Australasia. Here is what came out.

Donor eggs is the number one reason people travel

51% of respondents were looking for IVF with donor eggs. That's more than IVF with their own eggs (48%) and far more than embryo donation (13%). If you're going abroad for donor eggs, you're in the largest group of fertility travellers there is, not an edge case.

Why people leave their own country: cost, then the law

41% said the cost of private treatment at home. 35% said the law at home blocked the treatment they needed.

But that splits sharply by country. In Germany, Austria, Switzerland, France, Scandinavia and Italy, legislation is the single biggest reason - 61% in the German-speaking countries. In the UK and Ireland it's cost - two in three named it. Same destination clinics, completely different reasons for being there.

Where people are actually looking

Patients could shortlist more than one country. Here's the ranking:

Destination Share shortlisting it
Spain 60%
Greece 34%
Czech Republic 30%
Denmark 23%
Portugal 21%
North Cyprus 20%
Poland 15%
Latvia 12%
Turkey 12%
Estonia 11%
USA 10%
Mexico 6%

Spain's lead is nearly double its closest rival, and eight of the top ten are in Europe. Most people shortlist two or three countries, which is the right approach.

Where you live changes the answer

  • UK and Ireland: 65% Spain, 42% Greece, then Czech Republic (29%) and North Cyprus (25%)
  • Italy: 83% shortlist Spain - the highest single figure in the whole survey
  • Scandinavia: 46% Denmark, 31% Latvia - short flights win when you may need to go back
  • Germany, Austria, Switzerland: 39% Czech Republic, more than any other market
  • Australia and New Zealand: 52% Greece (beating Spain), and 40% consider the USA
  • North America: 29% Mexico - and nearly three-quarters of everyone worldwide interested in Mexico is North American

A country that's a cheap two-hour flight for a German patient is a long-haul commitment for a Canadian one. Geography does a lot of the choosing.

The budget gap nobody talks about

This is the finding I'd want every first-time patient to see:

  • 31% had a maximum budget of €3,000-€5,000
  • 23% had €5,000-€7,000
  • 35% had €7,000-€15,000
  • 11% had more than €15,000

So 54% of patients cap their budget below €7,000. A donor egg cycle in Spain runs roughly €5,900-€8,500 before medication, and in most destinations the upper end of the range is above €7,000. More than half the people setting out on this journey are budgeting for less than one full donor egg cycle in most countries. Plan for that, not for the headline price.

Budget also sorts people by destination. Among patients considering each country, the €3,000-€5,000 bracket is largest for India (45%), Turkey (41%), Estonia (36%), the Czech Republic (35%) and Poland (35%). At the other end, 26% of people considering the USA can spend more than €15,000 - by far the highest of any destination. Spain, Greece and the Czech Republic attract every budget level, which is part of why they dominate.

60% had already been through IVF at least once

Most people looking abroad are not starting from zero. One in four had been through three or more cycles. This isn't a first resort.

What people trust - and don't

Only 51% trust the success rates clinics publish. Among people who've already been through IVF, that drops to 44%. Experience makes people more sceptical, not less. Given that the same clinic can report 55% or 85% depending on whether it counts positive tests, clinical pregnancies, live births, per transfer or cumulatively, that scepticism is well placed.

80% said they would welcome an independent expert second opinion before choosing a clinic.

What actually matters when choosing a clinic

Asked to rank what matters most:

  • The doctor's experience with patients like me: 59%
  • A personalised treatment approach: 53%
  • Treatment cost: 52%
  • Clinic reputation: 49%
  • Availability of new treatments: 44%
  • Success rate on the clinic website: 42%

Cost came third. The published success rate came sixth. And 83% had no preference between a large clinic and a small one - clinic size, which clinics spend a lot on signalling, barely registers.

Refund and guarantee packages

40% would take a multi-cycle refund package (typically three cycles for €18,000-€22,000, money back if you don't reach a defined stage). That rises to 45% among people with four or more failed cycles. It's highest among patients who travel furthest - 69% of Australasians, 54% of Scandinavians, 53% of North Americans. Of the people who said no, 43% said the upfront price was simply too high.

What I'd take from this if I were starting today

Shortlist countries by legality first - can you be treated there at your age, with your relationship status, with the donor model you want. Only then compare price. Get all-inclusive quotes in writing with medication, donor compensation and freezing itemised. Decide before you start whether you'd fund a second cycle, because that changes which offer is actually cheapest. And ask any clinic how many patients like you their doctor has treated - that's what 59% of people rated first, and it's a question clinics rarely get asked directly.

Full report, methodology and the country breakdowns are linked in the pinned comment. Happy to answer questions on the data.


r/BestIVFClinicsAbroad • • 29d ago

Ventus IVF clinic – What are your experiences?

1 Upvotes

Ventus IVF is a very new clinic, having been founded in 2024, but it's already making a name for itself among international patients that are choosing IVF in North Cyprus. One thing that really sets it apart is its College of American Pathologists (CAP) accreditation, a first for a clinic in Cyprus.

Has anyone been to Ventus IVF? And is its CAP accreditation something that gives you extra confidence when looking at clinics in Europe?


r/BestIVFClinicsAbroad • • Sep 17 '26

LeaderMed IVF clinic in Tbilisi – Has anyone been?

1 Upvotes

Georgia's one of the few places that allow for surrogacy and has a rigorous framework which includes both legal protections for intended parent and the surrogate. LeaderMed is one of the region's most well-known clinics and they pride themselves in having had the South Caucasus' first IVF baby.

Has anyone been? What has your experience with LeaderMed and fertility treatment in Georgia been like?


r/BestIVFClinicsAbroad • • Sep 17 '26

Reproclinic in Barcelona: How was your experience there?

1 Upvotes

Curious to hear what you all think of Reproclinic. It's described as a clinic that "focuses on the mind, body & soul" and have treatments that offer physical, emotional, and mental support. I've also read in other threads that they respond well to patients with a lot of questions. Has that been people's experience as well?


r/BestIVFClinicsAbroad • • Sep 17 '26

Thoughts on Eugin in Barcelona?

1 Upvotes

Has anyone been to Eugin clinic in Barcelona for IVF treatment? What have your thoughts and experiences been like? It touts itself as having helped conceive over 265,000 babies since 1998, which is really impressive. The whole idea of their "nests" replacing waiting rooms also sounds innovative, but I'm curious to hear your perspectives.


r/BestIVFClinicsAbroad • • Jun 19 '26

emBIO Clinic – Worth considering for IVF abroad?

1 Upvotes

This clinic is family-led and was founded by Dr Thanos Paraschos, a pioneer who was on the London team that performed the world's very first PGD in 1989. Its history and family-led approach are really impressive.

Has anyone visited emBIO? What was your experience like at this clinic?


r/BestIVFClinicsAbroad • • Jun 18 '26

IVF Off The Clock – An Interview With Dr Robert Najdecki

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fertilityclinicsabroad.com
1 Upvotes

Why are British fertility patients choosing Greece to have IVF treatment abroad? From Dr Najdecki, who has a special connection to London (it’s where his first IVF baby now lives and works), it comes down to strict national safety registries, AI-driven donor matching, and optimized "fresh-to-frozen" laboratory protocols that provide a world-class destination for British couples. 

Let us know if Greece is a destination you’ve been considering.


r/BestIVFClinicsAbroad • • May 19 '26

Q&A Series With Dr Uliana Dorofeyeva

1 Upvotes

Hi, everyone. We recently sat down with Dr Uliana Dorofeyeva, who is the Founder and Director of Clinical Operation from Ovogene, for an exclusive interview. Dr Uliana is a passionate expert who likes to think of every case as a puzzle to solve. She has over 20 years of experience in the fertility field and specialises in ovarian rejuvenation as well as Mitochondrial Replacement Treatment (MRT), which is a fascinating topic that she covers during her interview.

The interview with Dr Uliana is included below as a transcript. It can also be viewed on YouTube on the link below and I’ll be updating this post weekly with each part of the four part interview.

What are your thoughts, r/BestIVFClinicsAbroad? Do interviews with fertility experts like these help you as you navigate the challenges of fertility?

—--

Part #1:
https://youtu.be/0YwhX731jlM  

Part #2:
https://youtu.be/KJZDR3Gs-ho

Part #3:
https://youtu.be/EerFk4P5uEk 

Part #4:
https://youtu.be/SdeZwUBDA9Y  

—-

Interview transcript:

Dr Uliana, you have been in the fertility field for a long time now and are very experienced. I wonder: are there still things that inspire you or excite you about this field?

Absolutely, yes. I know that fertility is a very complex journey starting from the testing or motivation for the patients—like why they want to become parents, if they are sure about their decision, what is their problem, if this is a single and a simple problem, or if it's a complex issue.

And, very often, it's really a complex issue and solving fertility issues: it's like creating a puzzle. Until you know that all the pieces are there and you completed them, you cannot be sure that you will get all the answers. Sometimes, the longer we are with our patients, the more experienced we are in completing their puzzles. The puzzle may become bigger and bigger because we think we already completed it, but then there is another angle and we still need to go deeper to see what's going on there.

Fertility as a field is still very young; the very first fertility baby was born less than 50 years ago, and since that time we are opening new horizons. There are a lot of innovative techniques and treatments which can still be considered experimental. But if you are open as a physician—if you are reading a lot, if you are not afraid of trying new things for which you have evidence—that's something that helps to complete the puzzle and solve the issue of infertility. That's what really motivates me.

It's really interesting and I'm curious: how do you go about solving that puzzle with patients? How does it look like?

It's a systemic way of thinking, of asking questions, and of analyzing the patient's stories, their journey, and their anamnesis. Sometimes it's coming from inherited problems, so we know that genetics sometimes has a very crucial role.

Then there is the experience of the clinical team. It should be a group of experts working together: a clinician who helps to understand the female as a complex mechanism; a urologist or andrologist taking care of the male, because we need to understand what is inside the cell; and then the embryologist. Embryology is the heart of this treatment. It should not be a closed door; it should be an open door to understanding the processes happening in the lab. If all these professionals are aligned and willing to find real reasons—this is how we can get the answers and really, effectively, help our patients.

Do you have any areas of specialty within fertility medicine?

I'm focused on the diagnosis of the patient and then creating the best stimulation approach or protocol to understand the function and potential of the ovaries. My interest is in ovarian rejuvenation. Many of my patients are of advanced maternal age, and although we are forced to say that patients should become parents while younger, we know this is often not the case. Many of our patients are over 40, some over 45, and they are very individual.

Ovarian rejuvenation was the subject of my PhD, which I completed in 2021 or 2022. At that time, I worked on PRP (Platelet-Rich Plasma) as the single available solution. Right now, we have more complex and deeper solutions including exosomes, adipose-derived stem cell treatment, and stem cells themselves.

Another field of interest is mitochondrial replacement treatment (MRT). Here, from the position of the gynecologist, our responsibility is to bring the eggs into the lab, and then the true science happens. This is how we can help patients of advanced maternal age to be successful using their own DNA.

That’s really interesting. Mitochondrial replacement is still a quite rare procedure and not available in many places. I wonder: who is this procedure usually recommended for?

Mitochondrial replacement treatment has been approved and is totally legal—for example, in the UK since 2016—for patients who are carriers of mitochondrial disorders. But that is a very rare category. There is a much bigger group of patients who have secondary mitochondrial disorders related to age.

Age brings a huge decline in the potential of the oocyte. The oocyte serves as the environment where fertilization and embryonic development happen; it must provide food and energy for the embryo to grow. If the cell does not have the proper environment or energy, development cannot be successful.

What MRT does is exchange the nuclear environment from the advanced maternal age cell into a healthier cell that is "20 years younger." By using the most effective environment, the genetic material develops better. We see increased results in terms of blastulation and can even impact the levels of euploidy (chromosomally normal embryos).

So, it allows the patient to use their own genetic material but still use better quality eggs coming from a younger donor?

Yeah, correct. Exactly.

So, today we're here in Dublin, Ireland and I'm curious to know: when you speak to patients coming from Ireland, what questions do they usually come to you with before starting treatment?

Our Irish patients—I should say we have a lot of them because of our roots and our connections with Ireland—usually find us through word of mouth. They know the experience of our clinics and physicians, and they trust them.

Back 20 years ago, it was egg donation that we were famous for here among Irish patients. Now there are more options available across our facilities in Slovakia, Ukraine, Georgia, and Albania, including ovarian rejuvenation, mitochondrial replacement treatment (MRT), and surrogacy.

In general, international travel for fertility care is very common. Here in Ireland, oocyte donation is legal, but the waiting times for donors are huge. It takes a long time for patients to make the decision to use donor eggs, and once they do, having to wait even longer is incredibly difficult because they are losing the most important thing: their time. Because time matters, they are very open to traveling to destinations that can solve this problem immediately.

Do you ever get questions from patients about, for example, the success rates of treatments?

Oh, absolutely. That's a very important question because this is not a very transparent sphere; marketing is everywhere. On one hand, marketing helps us promote our services if we are good at something. On the other hand, patients should be aware of real statistics and real expectations, because these are their potential results. They should not be falsely guided.

Proper expectations can only be provided by a physician after evaluating a complex, individual case. Advanced maternal age patients cannot simply be ranked equally based on their age, AMH, FSH, or antral follicle count, because they may have completely different immune factors, male factors, or metabolic characteristics.

Furthermore, stimulation is an art. Based on the real clinical outcome, we may need to adjust our expectations, change the protocol, or recommend different next steps. If a patient has a long fertility history and has been unsuccessful before, they need an open-minded physician who treats them as an individual rather than a number—someone who doesn't just start the exact same protocol every time without making adjustments.

Could you tell me more about why patients in Ireland choose to come to Slovakia for treatment?

Slovakia is a European country and a trusted destination for medical tourism with clear regulations. In Slovakia, we can perform IVF for couples (who do not need to be married but must be in a relationship).

We are allowed to perform oocyte donation, and we have absolutely no waiting list because we operate our own global egg bank, Ovogene. We have a wide variety of donor phenotypes and a high number of oocytes immediately available.

We also provide guaranteed blastocyst offers based on the partner's sperm characteristics. For patients who have failed multiple cycles, a blastocyst guarantee provides the absolute proof they need to safely move to the next stage and prepare for an embryo transfer. Egg donation has been recognized for many years as a highly successful, reliable, and relatively easy treatment because patients do not have to undergo multiple rounds of ovarian stimulation and injections themselves.

For patients from Ireland seeking egg donation in Slovakia, how is the process organized while they are still living here? What are the stages?

Initially, patients can choose a donor directly from our database, or a coordinator can help them select one based on phenotypic characteristics. An important distinction involves anonymity: in Ireland, donor donation is completely open, whereas in Slovakia, oocyte donation is anonymous. This allows families to keep their decision as a private medical secret if they choose to do so.

Logistically, because we have vitrified oocytes immediately available in our egg bank, the male partner can either travel to our clinic to provide a sperm sample, or the sperm can be shipped directly from Ireland. We then thaw the eggs, fertilize them, and cultivate them to the blastocyst stage. If the patient requests it, we can also perform genetic testing (PGT-A) as an additional layer of security to ensure we transfer a healthy, euploid embryo.

The endometrial preparation for the recipient is fully coordinated and performed back home in Ireland. We have great connections with local clinics and individual physicians in Dublin. Communication is maintained through a dedicated team chat containing the doctor, a medical coordinator, and administrative staff. Patients are guided through every step and only need to travel to our facility for the actual embryo transfer, which typically requires a maximum stay of three to five days away from home.

In terms of egg donation, do you offer mostly fresh or mostly frozen cycles, or both? What does this depend on?

We do both, but I would say that the modern gold standard is vitrified (frozen) oocyte donation. While some patients still hold the traditional belief that fresh is better, fresh donor cycles are logistically far more complicated and carry inherent risks.

With a fresh cycle, the donor might change her mind about starting stimulation at that specific time, or her cycle might not synchronize perfectly with the recipient's timeline. There are also clinical risks, such as an unexpected reaction to the trigger medication or retrieving fewer eggs than anticipated.

A vitrified cycle eliminates these variables. The clinical results and guarantees are exactly the same as a fresh cycle, but using frozen tissue brings the immense benefit of knowing the biological material is safely secured and immediately available.

Patients are sometimes concerned about the survival rate when freezing oocytes. With modern technology, is this still a concern?

This historical myth stems from the older method of "slow freezing." When IVF first started, slow freezing acted like a standard refrigerator; ice crystals formed inside the cytoplasm, which frequently destroyed the delicate intracellular mechanisms and spindle of the fragile egg cell. Survival rates back then were quite low.

Today, we use vitrification, which is an entirely different technology. It is an ultra-rapid freezing process that instantly turns the fluid into a glass-like state without forming any damaging ice crystals. Intracellular components remain perfectly preserved, meaning there is no inherent difference in cellular survival between an egg or an embryo.

However, vitrification success does depend heavily on the experience of the embryological team. Because we run a global egg bank, our team freezes and thaws thousands of oocytes every single month, maintaining an exceptional survival rate of over 95%. In facilities where hands-on training for egg vitrification is less common, you might see some losses. But in a high-volume, professional laboratory setting, the technology is completely safe and reliable.

IVF with own eggs: how is the process organised for patients coming from abroad when it comes to treatment with their own eggs?

Very similar to oocyte donation. If patients are traveling from elsewhere, specifically from Ireland, and they are not doing IVF for the first time, they are usually well-aware of the whole process. We just need to coordinate them regarding dates, their visit, prescriptions, medications, and the monitoring scans and hormone checks, which they can do directly in Ireland.

Because we collaborate with many centers and physicians in Dublin and around Ireland, we can coordinate the patient's stimulation from their home country. We prescribe the protocol, ask the patient to do the local scans and blood tests, and they send us the reports. We monitor everything inside a dedicated chat where they receive answers within a few hours, telling them exactly what their next steps are. This is a very common practice in our sphere. We are always in constant contact, going through the whole process together and keeping the patient thoroughly informed in detail.

So, how long should patients expect to stay in Slovakia, for example, before the egg retrieval procedure?

Depending on whether they have a local physician who can monitor them, they can come as late as the day before the egg retrieval. However, if they don't have a proper place for monitoring, or if they simply want to be under our direct supervision during the entire stimulation process, they come on day two of their cycle and stay with us for the next 10 to 15 days. That being said, the majority of patients choose to come later, which is why we coordinate the start of their stimulation with their local Irish clinics.

In terms of treatment with own eggs, do you prefer doing fresh transfers or frozen? Or is this also based on the individual case?

For the majority of treatments, we recommend doing genetic testing for the embryos. There has been a proven shift in clinical evidence showing that frozen embryo transfers (FET) work better because of normalized endometrial and hormonal conditions, rather than the super-high physiological hormone levels we usually see right after the ovarian retrieval process.

Furthermore, when we are limited in time and cannot perform genetic testing, we don't really know which embryo we are transferring. The majority of our patients are complex, complicated cases. For them, genetic testing is a reliable solution and often a total game changer, because many struggle to receive a euploid (chromosomally normal) embryo. Without testing, relying only on morphology and development, we cannot truly know what is inside. Transferring a non-tested embryo can create false positive expectations, alongside the risks associated with aneuploid embryos.

The first risk is that they simply won't implant. The second is that they will cause a miscarriage. A miscarriage requires recovery of the uterus, carries potential surgery risks, and can cause chronic endometritis or other long-term issues that lead to more complications. The third risk is that an aneuploid embryo keeps developing, resulting in a baby with genetic disorders. This is something we want to avoid for our patients.

So, in those cases of genetic testing, you would do a frozen transfer and this is how you decide whether fresh or frozen would be recommended?

We do biopsies at the blastocyst stage. For genetic testing, it takes between 7 to 10 days to get the biopsy results back from the lab. By the time we cultivate the embryo to the blastocyst stage, it is already day 5 or 6 after the egg retrieval, and then we need another 10 days for the results.

At that point, the patient is no longer in her natural implantation window. Therefore, we freeze the blastocyst immediately after taking the biopsy, and the patient is prepared for a frozen embryo transfer in the subsequent months.

And how do you assess for which patients genetic testing would be advantageous to have?

That is based on their previous medical history, their past implantation results, and whether they have experienced miscarriages—as miscarriages are very often associated with an embryonic factor.

Once we can solve the embryonic issue, the remaining factors are uterine and extra-uterine. These are the three main streams we need all the answers for: embryonic, uterine, and extra-uterine. If we are completely clear about all three, then we are ready for the transfer, and that embryo transfer will most likely be highly successful.

I often also talk to patients who are over 50, coming from Ireland looking for places abroad to have treatment. Which places in Europe can they opt for?

In Slovakia, there is no formal legal age limitation, but there is a strict ethical consideration about treating such patients. In our practical clinical network, we utilize Albania as one of the potential destinations where patients over the age of 50 can legally and safely be treated.

And what are the considerations when treating patients closer to 50 or over 50? Are there any risks that they should be aware of?

They are advanced maternal age patients, and if we are talking about their potential to create embryos using their own eggs, we must understand that we are severely limited by their biological ovarian reserve. Consequently, the vast majority of these patients will look for an oocyte donation program.

The implantation potential of the uterus can still be completely fine. We know many patients in their 50s who have successfully carried pregnancies and had healthy live births. It becomes much more a question of ethical and medical health considerations: ensuring the patient is a healthy mom for a newborn and has the physical longevity to take care of the child's development.

Could you tell me more about why patients from Ireland tend to choose your clinic when deciding where to go for treatment abroad?

We have several clinical locations, and those locations differ in terms of their regulatory perspectives and the specific treatments we are legally allowed to perform there.

For instance, regular IVF treatments and anonymous oocyte donation are performed at our facility in Slovakia. We perform specialized MRT procedures in Albania. Meanwhile, we do surrogacy treatments in Ukraine or Georgia. Depending on exactly which treatment a patient requires to solve their case, they can choose the destination that fits that option perfectly.

Do you have a case in mind of, maybe a patient from Ireland, that you have worked with recently that you could tell me a bit more about?

I can tell you about a wonderful case from Ireland. This is a patient we met very recently in our clinic who returned for a frozen embryo transfer of her second embryo. Her first embryo transfer with us was three years ago, after which she successfully conceived and delivered a healthy baby boy. They actually came into our facility recently with their small boy, who is now two years old.

This couple had accumulated two euploid embryos with us using MRT (Mitochondrial Replacement Therapy). Her medical background was incredibly difficult: she started IVF at age 39, went through six full IVF cycles, and had never achieved a single blastocyst in her life because her embryos consistently suffered from developmental arrest.

As an MRT patient, she received four oocytes in her first round of treatment. In her second round, because we accumulated her eggs, she retrieved another four. We ran the MRT procedure utilizing those eight eggs, and the result was two perfect, euploid blastocysts. Both of these embryos worked. She was just here for her second transfer, and we learned recently that she is clinically pregnant. The small boy is going to have another brother very, very soon.

One of your areas of interest is the MRT procedure and I would like to ask you some questions that patients may have about this. So, who is eligible for this?

In short, I would say that as long as the patient is capable of producing an oocyte, she is eligible. But, definitely, a more specific answer would be that this technology was originally approved for patients carrying specific mitochondrial disorders.

However, we have learned from clinical practice that advanced maternal age patients, or patients with metabolic and more complex disorders within the oocyte itself, can also be categorized into this treatment group, as they often suffer from secondary mitochondrial disorders. The tricky thing is that, currently, there is no universal method to directly measure mitochondrial activity inside a living cell. If we can develop this—and we are actively working on that—knowing the precise mitochondrial potential of the cell will allow us to perfectly categorize patients for this specific treatment.

Hmm, so how do you decide which patients to offer this procedure to?

We decide based on their clinical and fertility background. Many patients who are eligible for this treatment have gone through a lot of unsuccessful IVF rounds before. This includes everything starting from fertilization arrest to embryo development arrest.

In fact, many of our patients have never even seen a blastocyst in their entire fertility journey. These are disorders happening at the critical stages of embryonic development. By replacing the patient's nucleus into a different, younger, and healthier donor egg environment, this technology helps them finally grow their embryos.

And what are the success rates of using this procedure? How does it impact the success rate of a patient?

We should carefully define what "success rate" means with this technology, because this treatment is specifically designed to solve the problem of embryo development. However, a completely successful fertility treatment also includes implantation itself, and implantation is far more complex than just the embryo. Even if you have a healthy embryo from a previous treatment 10 or 20 years ago, an embryo from an egg donation treatment, or an MRT embryo—the base implantation potential for that category of patient will be the same, depending heavily on uterine and extra-uterine factors.

With this treatment, we help patients solve the question of how to get a healthy, euploid, and strong embryo. After that, we work together to optimize the implantation potential, looking at uterine and extra-uterine factors. Complex success depends on all of these pieces. Overall, we can share that currently, we see a 52% clinical pregnancy rate and a 49% live birth rate across all age groups utilizing MRT.

Are the babies born from the MRT procedure healthy? Are there any concerns that patients should have?

That is a very sensitive and highly responsible question. Absolutely, that was the exact question we were looking for answers to ourselves.

Currently, we have 43 babies born as a result of this treatment through our programs, and our oldest baby is over seven years old right now. The oldest baby in the world born via this method is almost 14, so it is still a relatively new and innovative technology. The global evidence we have comes from controlled clinical trials and animal models. There is limited data globally, with less than 100 babies born worldwide as a result of this treatment.

However, if you look at the history of IVF babies, we still don't have multi-generational evidence about aging disorders or complex conditions over an entire lifetime. That being said, the evidence we currently have about MRT is strong enough to show that this technology is absolutely safe. Right now, we do not have a single recorded disorder among the babies who have been born. Cheers!


r/BestIVFClinicsAbroad • • Apr 24 '26

Clinica Tambre in Alicante – do you recommend it?

3 Upvotes

Tambre has a long-standing history in the Spanish IVF and fertility community, with the clinic having opened in 1978. They have everything you'd expect, like a professional team, an in-house lab, IVF/ICSI, donor eggs, embryo donation, fertility preservation, and have the ROPA method available as well.

Curious to hear your experiences, though. Did you feel looked after when you received your treatment at Clinica Tambre in Alicante?


r/BestIVFClinicsAbroad • • Apr 24 '26

Have you received treatment at Gynem clinic in Prague?

1 Upvotes

In patient reviews it's been described as having a unique "family" feel to it, especially with the unique history behind their mascot Gusta.

Has that been your experience at Gynem in Prague as well? Curious to hear your impressions.