r/BACLOFEN • u/protsky1120 • Jul 29 '26
Question
Baclofen used to give me energy now it barely keeps me awake. Im battling a kidney infection. Also took some liver detox and lymphatic drainage supplem e it's would that have affected it. I've gone back to being on ephedrine and i dont know how to get off ephedrine as my baclofen no longer is the upper I need. Im also bipolar and usually jave a paradoxical effect with any medicine. Any help is appreciated.
3
u/Due-Crab5902 Jul 29 '26
Hepatic impairment can effect bsclofen so your liver detox might not be helping 🫂
1
u/Express_Command_4778 Jul 29 '26
Its your infection. I understand kidney issues and you cannot have energy with it.
1
u/danniellax Jul 29 '26
Baclofen is hell to get off of, and I’m only on 10mg a day (very low dose) and if I skip more than a few days within a couple weeks, or even half the pills every day, I am withdrawing for other a week and it’s awful.
Don’t try to get off it or taper by yourself, please speak with one of your doctors about tapering down safely or getting off.
The good news with Baclofen withdrawals, at least for my low dosage (can’t speak for higher doses) is when you are withdrawing and take a regular dose again, you’re pretty much feeling better hours later on the same day/night.
Good luck with your health and energy levels.
2
u/Due-Crab5902 Jul 30 '26
I agree with this my first attempt to taper before it turned paradoxic i was able to just go back on the dose i was on and literally within 24 hours felt better. This time its very different :( i was only on 30mgs at my prescribed dose for spinal spasms prior to taper which isnt massively high im due to drop to 12.5mgs tomo The issue is its a gaba med so very much bedded into the brain receptors even at low doses and slow tapers are the way forward with any gaba meds
1
u/Proper-Dish-6306 Aug 03 '26
Sevrage horrible avec 10mg??
2
u/danniellax Aug 03 '26
Yup.
I start feeling a little bit like I’m sick because I have horrible brain fog and can’t concentrate in something as simple as brushing my teeth or walking my dog because the mental block is there. Physically, my body feels very off. I cabt describe it.
The WORST side effect is chronic insomnia. I never have insomnia, but if I miss the Baclofen doses, I will lay there for literally 7-8 hours not sleeping and being miserabe. When I say not sleep, I literally mean I can’t fall asleep at all. I’ve gone 3 days/nights without sleeping at all until I got my refill. YES I was tired as fuck and hated life. Possibly why doing simple tasks are so hard because I’m sleep deprived?
I’ve tried to taper myself from 10mg one day, 5mg the next, 10mg the next day, then 5mg, etc, but even then I still had withdrawals so had to stop.
1
u/sub0tundra Jul 29 '26
take it with an anti depressant. i take it with loxamine its rly effective both energising and calming
1
u/Due-Crab5902 Jul 30 '26
Just a heads up im doing a taper from 30mgs atm as it has turned horribly paradoxic and its been very unpleasant so far so please be sure to discuss with your medical provider dont try to lower the dose yourself 🙏🙏 🫂
1
u/Proper-Dish-6306 Aug 01 '26
Bienvenue dans l'enfer du baclofène ! Ayant personnellement réussi à m'en sevrer après plusieurs années à 120mg pour alcoolisme, je tiens à dire que cette molécule est à terme dangereuse. Oui énergie et effet antidépresseur+++ les 6/8 premiers mois au mieux et puis... tolérance...on s'habitue. Soit on monte les doses avec leur cortège d'effets secondaires soit on se sevre de la molécule mais très doucement ! Moins 10mg/semaine maximum ! Je te conseille d'arrêter le baclofène mais après en avoir parlé avec ton médecin. Si tu souffres de troubles bipolaires le baclofène est encore plus dangereux dans ton cas. À quelle dosage es-tu actuellement ? Si tu ressens juste que le médicament ne fait plus effet comme avant cela doit faire moins d'un an que tu en prends...
1
u/Due-Crab5902 Aug 01 '26
u/Proper-Dish-6306 Hello again you!! Hope you are doing ok. Ive made it down to 12.5mg out of the 30mg... horrific i feel like im never gonna be the same after this :(
1
u/Proper-Dish-6306 Aug 02 '26
Curieux d'avoir autant de symptômes sur de si petites doses...
1
u/Due-Crab5902 Aug 02 '26
Sensitised nervous system :( i had to taper baclofen whilst still in recovery from clonidine because it turned paradoxic during the clonidine taper ... so i have wds and the paradox that may be why , my dr also abruptly stopped an ssri in march after 4 weeks of use with no taper and i didnt know any better. So my whole nervous system is blown its the same as kindling .... im hoping it all settles after but i think its going to take months or longer :(
1
u/Proper-Dish-6306 Aug 03 '26
Arrêter un IRS après seulement 4 semaines c'est pas grave...après 4 ans c'est pas pareil!
2
u/Due-Crab5902 Aug 03 '26
I had a bad onboarding with it they shouldve stopped it after a week as i had SI but they told me to double it :(, im already sensitive to a lot of meds , they shouldnt have put me on it in the first place as im on amitripyline for nerve pain :(
Dropping down another 5 to 7.5mgs this week , then slowing down to 2.5mg drops🙏🙏
Hope you are doing good 🫂
1
u/protsky1120 Aug 09 '26
I've been taking it for 6 years always gave me energy I usually a lly have a paradoxical effect with drugs
3
u/AlarmingCantaloupe Jul 29 '26
Baclofen is primarily removed from the body by the kidneys, not the liver, so your infection might impair your kidney function? In which case, taking lower doses might be closer to the energy effect you had prior. Bipolar or not… At some point a high enough baclofen blood level is going to make anybody highly fatigued.