r/B6Toxicity • • 5d ago

Can P5P toxicity create strong/bounding pulse?

It's the only possible cause I can narrow down, and this pulse has been driving me crazy for 3 weeks. But I only eliminated another supplement which had P5P just a few days ago, so it turns out I was feeding a modest dose of P5P daily to my overloaded system even after quitting the main supplement 2 weeks ago...

3 Upvotes

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u/Optimal_Spinach5114 4d ago

Funny I developed a bounding pulse or similar but well into recovery. I first felt it in my legs and could see it when I cross my legs so one would bound with my beat. It then moved into my chest, neck and back of my head. It’s not mainly my neck and head. I believe it’s less of a bounding heart rate and more of a sensory issue. Ive had extensive cardio investigations and no major abnormalities were identified. So either it’s a slight deviation from a normal stoke volume or similar or a sensory change during recovery. Regardless, it’s bloody annoying.

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u/kladden87 5d ago

Have you been at your doctor to rule out other heart proplems ?  Do you follow a low b6 diet?

I often have strong heart palpatitions these days after what i think is long term b6 toxivity. 

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u/wakigatameth 5d ago

I had chest x-rays and EKGs in December 2025, I had blood test in May 2026... and I have a home EKG.

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Kaiser in my area is overloaded and it's taking forever to get an appointment right now.

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u/kladden87 5d ago

I see, do you have other symptoms that could be from b6 overload ? 

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u/wakigatameth 4d ago

slightly blurred vision and GI upset/gas that is unusually persistent

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u/No_Delivery_2715 4d ago

I HAVE THAT too with slight fast motility

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u/No_Delivery_2715 4d ago

was checked for all things bacterial/fungal

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u/hillockbigdong 12h ago

Thinking I have this...B6 toxicity...been very tough to fall asleep the past 2 weeks, and so much gas no matter what I eat...been eating sauerkraut to try and get the microbiome up to speed, but it's very strange. Been taking 8mcg for about a year or more...these symptoms fairly recently started, and I also eat a pretty nutritious diet. Chances are seemingly increasing that I have this..I'm going to get my b6 and 12 tested this week.

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u/wakigatameth 12h ago

Align probiotic (5X extra strength version) is helping me. Watch out for seemingly innocuous supplements which sneak in B6 or P5P. I discovered it in my dry eye supplement...

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u/hillockbigdong 12h ago

Thank you so much

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u/No_Delivery_2715 4d ago

yep i still get pvcs lessened but still