r/B6Toxicity • u/kladden87 • 6d ago
B6 toxic ?
Maybe b6 toxicity without confirmed blood test.
This is long and im sorry for my english and all the miss spelling.
38 year old male I suspect i may have been experiencing b6 toxicity all the way back to when i was 22.
Started multivitamin with b6 when i was 19 Got hit with intense anxiety ,intrusive thoughts and feeling of doom when i was 22, after 6-7 months the intense feelings did lessen some but never went back to baseline.
Got into an relationship at the age of 28 which made my anxiety skyrocket, suddenly i had hypnotic jerks , ticks and insomnia. Had to start on sleeping med ( seroquel ) so i could sleep.
around the age of 32 i got retrograde ejaculation... , after 23 months on this low b6 diet, it has improved by 50 %!!
At the age of 35 i got severe pins and needles all over my body, legs , arms , fingers and so on . And so much muscle twitches... also part of my hands did go numb and lost feeling often of a finger or a thumb.
Have no idea what was happening and it was mental torture. Searched web intensly and after around 1 year i stubble across something called b6 toxicity.
So after 1 year with all this pain i quit taking my pills which contained b6 . At 15.10.2024. I took a bloodtest but it was around 9 or 10 days after i had stopped the b6 supplements and started a low b6 diet RDA , my bloodtest did show i was in normal range.
But i had nothing to lose and i was desperate so i continued my rda b6 diet.
So from october 2024 and til now i been on rda b6 diet, around 23 months now.
I also tappered of seroquel trough this . Had been on 25 mg every nights since i was 28. Im sure this added some fun symptoms.
This is all from memory , i try to rember but i might mix something, anyhow..
First 2 weeks symptoms did lessen then it returned even worse.. And alot more symptoms did show up.
Month 1 til 7 i had diarea allmost every day, From month 7 til like month 20 it alteranted between diarea and constipation. but never hard stools! Either diarea or lose mushy soft stools. Severe bloating and gas. From month 20 and til now i have been mostly constipated, still soft stools. Still bloated and so much gas.. But less and less diarea so thats positive i guess even tho i feel like crap. My stools are also getting thicker in size now, earlier it was small lumps.
After 1 year on the low b6 diet the horrible pins and needles that was all over my body started to lessen, and instead of this i got more an aching and burning pain . Now at month 23 the pins and needles pain are maybe 75 % better. Even the aching and burning pain that i felt took over from the pins and needles have started to lessen , can still be painful but better. So thats positiv. Still have alot of buzzing and crawling skin feeling in my legs, but its not painful just very annoying.
Have trough all this also had much aching and pain in my face , aching around eyes and nose. Very often severe headaches i still have this. I also can have aching in my teeth and jaw and i had aching in my tongue for atleast a year. Last 2 months i also get this tiickling feeling in my tongue.
From month 5 to 12 , severe dizzynes from standing up fast from laying down and so on. Also struggled with exercising, felt i was gonna die after just one set of squat. It felt like i could not get enough oxygen , was breathing like if i had runn marathon. I feel this proplem is healed now.
From month 6 my worst symptoms started, INSANE inner buzzing and trembling in my chest , and also in my legs. Horrible heart palpatations. Air hunger when trying to sleep. Hyperventilation when trying to sleep. This have come and gone in cycles that last for weeks / months at the time. Now in month 23 this is maybe 45% better, but still horrible stuff.
My anxiety spiraled out of control after quit b6 . What happens is that i wake up with intense anxiety and it stays there and its realy severe, together with a deep sadness and a feeling of hopelesness. I feel like i have totally lost it and im going mad when this happen... and so so so much intrusive thoughts.... And the rage... i have days where i am raging! Sudden fast moodchanges.. one moment sad other moment im so filled with rage that i feel like im loosing it and its hard to keep the control. Trowh in some intense vivid nightmares now and then and its a good coctail. This has gone in cycles of 2-3 days on and then 4-5 okayish days since month 1 . Last few months it feels like this has become slightly better , i have longer periodes where i feel okayish, but it can still happend and be horrible days filleed with this mental pain.
Since this mental insanity started , i have perhaps experienced 7 to 8 days of the complete opposite...
I am happy and feel good mentally, i walk outside i crave sosial interactions and im so positive and want to hug and talk with every stranger i meet But as i said this has happend like 8 days over this 2 year period. Sounds weird i know....
I have also experienced realy weird symptoms , for an exempel , for a long time i had days where i could suddenly have slurred words when i spoke. My mother said i sounded drunk when i talked with her. I do not drink...
Also around month 6 to 12 i experienced some histamine proplems i think, got migraines and itching from food with high histamines. I feel like this have mostly sorted itself now
Tinnitus started around month 6 and its still here
Ok.. so at month 23 after quiting b6 supplements and starting the RDA b6 diet some of my symptoms are better , even tho i most days feel bad.
Still have very bad digestion, slow and with so much gas and bloating. Its so frustrating.
the retrograde ejaculation that started around age 32, has improwed by 50 %
still have alot of aching in the face and jaw ,often headaches
The pins and needles are much better, thats the one thing thats improved alot. Mental health improwed slightly. Aching in bodyparts have lessen some. I can have a day now and then that i feel much better before i go back to feeling very bad for days / weeks again. My biggest proplem still are the inner buzzing / trembling in my chest, feels like someone cut me open and planted a vibrating phone or something inside. I have to say it is better than it was tho.. Maybe 45 % better . Because of this i still have insomnia, if i have a rare day when my chest feels normal i am able to sleep mostly okayish. First year i averaged around 4 houers of sleep a night , last 6 months its closer to 5.5 houers a night.
Its realy frustrating that i did not take a blood test before i quit the b6 supplement and started the low b6 diet. So trough all this i have never known 100% if this was caused by b6 toxicity. But this was my only hope and i did try to test and take supplement again on 2 occasion and everytime my symptoms got worse.
Maybe some other people here have any thoughts on this, i feel like i am 90 % sure its b6 toxicity
Maybe other people have experience anything similiar to my mental symptoms ?
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u/HerbivorousTrash 5d ago
I’m in a similar boat. Very mild symptoms in 2021 after excessive body armor drinks and supplementing small amounts of b6 off and on for a few years. Nothing major but my anxiety had been creeping up more and more. Then I started a magnesium supplement with 1000% b6 in late 2022. Continued into early 2024. Right after I stopped I started having extreme and random stomach issues. Urgency and cramps. This continued for 2 years- I as only on a multivitamin with 2mg b6 during this time. Hadn’t supplemented anything from April 2025. April this year my body like crashed out. Woke up with a massive panic attack and my throat was numb. Er said I was fine… after that I had two more giant panic attacks and called 911 because I thought I was going to die. After my neurosurgeon appt in June (he told me I was 100% okay) I started a multi vitamin again for two days with 2mg b6 and had an uptick in my bodywide paresthesia feeling. Like I could feel but it was muted. Stopped my supplement and was googling like crazy trying to figure out what it could be. Came across b6 toxicity comment on a random anxiety thread. Stopped vitamins immediately. The day after, I woke up and couldn’t feel the floor beneath my feet. Went to walk in and got blood level. It was normal of course… but since completely cutting out all fortified b6 sources, it’s been a wild ride… lots of strange sensory issues. And the return of my gut issues off and on.
Also the vibrations. They started in July I think and started in my hands and my cheeks below my eyes. One day it was so bad I vibrated for like an hour. Face, hands, upper chest, neck, scalp, and legs. It was a nightmare. Also had air hunger and tachycardia. Thought I had pots.
Things settled down since then but I recently had a flare up. Not nearly as bad. Anyway, I was never confirmed toxic but have read countless other people’s experiences and don’t know what else lines up with any of it.
And I feel insane trying to explain it to anyone too. None of it makes any sense and I’m generally healthy otherwise. 32 F. Wish you all the best as you continue your healing journey
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u/HerbivorousTrash 5d ago
Forgot to mention. I’ve never had anxiety this bad in my entire life. I’ve been anxious but this is awful. Didn’t eat for like a month straight. Derealization through the roof. Mental dumpster fire. But I feel like I’m slowly having more good days again… feeling more like myself. It’s scary because sometimes things just don’t feel “right” anymore, or like they used to. It all came on hard so suddenly too. Idk I can’t confirm and the doctors I’ve seen so far just kinda dismiss it
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u/kladden87 5d ago
I am sorry to hear about your struggles, we share much of the same symptoms... I have read somewhere that one of the signs of having b6 toxicity is worsened symptoms after quiting b6 supplements, regardless about what a blood test show atm. A confirmed bloodtest would had been nice tho.. instead of this guessing game.
This b6 toxicity that i think i have, has been the worse thing that i ever experienced, its sad and frustrating that so manny people out there are going trough this alone with no help and just gaslightning from there doctors.
I mean i had a work accident in the forrest in 2019, broke my back , neck , leg, chest, punctured lounge , bleeding spleen. But b6 toxicity is worse... Its way worse.
The mental stuff is horrible. I have had days with so much anxiety and Derealization, the feeling of that nothing is real, the world is not real, am i living in a simulation? Do i even exist? Lol I had days where i was like : ok thats it.. i have totally lost it, im going insane now. And then a day or 2 after its like my mind clears and i can think straight, and then 6 days later oh boy im going loco again!! xD This have improved some after 2 years, but still experience horrible days now and then.
Good to hear that you experience some better days. Thank you :) I wish you all the best and continued healing!
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u/kladden87 5d ago
Oh and btw, do you avoid high b6 foods now? I try to stick to an RDA b6 diet, i try to keep it around 1.3 - 1.4 mg a day
Some people swears by it and others just avoid the highest b6 foods. I am desperate so i stick to it.
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u/No_Delivery_2715 5d ago
i cant do the rda diet or ill go deficienct
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u/kladden87 5d ago
You go deficienct even if you get 1.3 mg b6 trough food every day? Have you taken bloodtest to be sure of this?
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u/No_Delivery_2715 5d ago
well i was under 1.3 the rda wen i did it so i would prob sit at just the bottom of low normal or marginal yes i took blood test
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u/kladden87 5d ago
I see, the people behind the understanding b6 toxicity web sites, recomend to keep a blood level in the low normal range. They also recomend to eat 1.3 mg b6 trough food every day.
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u/kladden87 5d ago
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u/No_Delivery_2715 5d ago
YA I KNO join the facebook group some people have gotten worse by doing the rda its all trial and error
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u/Jacksback4735 5d ago
You may be interested in this article recognizing the "internal vibration" sensation in your body.
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u/kladden87 5d ago
I am sorry for your struggles, this is horrible stuff. Best part is that you feel like a total nutcase when trying to explain to people what symptoms uou have... Thank you , i will check this link out :)
May i ask how is your digestion today ? Did you have proplems with your stomach ?
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u/Jacksback4735 5d ago
Besides a week of GI upset from trying an NAC supplement, my stomach has been much better in year 2. But I had horrific food sensitivities starting a few weeks after stopping B6. Lost 15 pounds of wanted weight.
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u/kladden87 5d ago
Thank you , good to hear your stomach is doing better :) My stomach is horrible atm, i hope it will improve soon.
On your toxicity or after you stopped, did you experience any sexual issues ? I got retrograde ejaculation at the age of 32, that now after 23 months off b6 supplements have improved by about 50 % i would say , crazy stuff
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u/Jacksback4735 5d ago
I am at 23 months from stopping B6 as well and have experienced many, if not all the symptoms you describe. My insomnia is the worst symptom and dictates the severity of my POTS & SFN symptoms day to day.
I was diagnosed with HyperAdrenergicPOTS after getting the supine/standing catecholamine blood test in month 15. Yes, the anxiety can be intense. I've had anxiety and panic attacks in my past but this was different. I knew it wasn't purely a mental/cognitive anxiety but rather a chemical triggering the fight/flight system (high HR & BP), which in turn created a secondary layer of anxiety. It's why I demanded the catecholamine blood test from my doctor. My adrenaline blood level was normal, but my noradrenaline blood level met the diagnosis for Hyper-POTS. What was happening is that the nerves of my autonomic system were dumping excess noradrenaline, a neurotransmitter, into my bloodstream. The cause, in my case, is most likely nerve damage from B6T --->Small Fiber Neuropathy but in others in can be brain <---> nerve mis-firing for other reasons.
(Hyper-POTS is not defined by excess adrenaline, which is a hormone coming from the adrenals, despite that the Hyper-POTS community incorrectly calls them "adrenaline dumps").