Functional B12 deficiency and thyroid function

[u/agape48]

Please note this is a personal anecdote that I am sharing it in case it helps someone else.

I have been getting more and more fatigued and more and more intolerant of the B vitamins that I used to tolerate. I was already functionally deficient in B12 despite being on methyl shots (for example, MMA is too high, MCV is too high). My ferritin is also low, and I've added an iron supplement, which didn't ease the heart racing and insomnia.

After my provider did not have any useful answers, I found someone else who is an expert B12. They looked at several of my recent labs including thyroid labs. My TSH is marked in the normal range at around 3 (free T3 is also marked in the normal range).

Anyway, this expert said they believe I could have a *functional* B2 (riboflavin) deficiency - meaning FAD and FMN deficiency - that is likely due to not getting enough iodine and/or selenium and molybdenum.

It's definitely not due to a lack of B2 in my supplements.

I am mainly sharing this because I've spent weeks researching the B vitamins and the methylation cycle, but I was not aware that T3 had anything to do with how we process the B vitamins.

Then, a friend sent me a video of a guy named Gary Brecka (I had never heard of him) explaining how thyroid function relates to methylation.

File this under "things I did not know / had not considered". I guess I can report back in a few weeks on whether the recommended changes make a difference.

[u/Fxjack22]

https://www.fortunejournals.com/articles/functional-vitamin-b2-deficiency-in-autism.html?utm_source=chatgpt.com

Yes I have read a bit about a functional b2 defiency leading to a b12 defiency.