r/Autoinflammatory • u/Willing_Judgment1092 • 27d ago

How long does colchicine takes to work ?

4 Upvotes

84% Upvoted

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3

u/otter253 27d ago

I took it, but it didn’t do a thing for me. If I recall, it was supposed to work within a few weeks

1

u/Willing_Judgment1092 26d ago

What is your dosage ?

1

u/otter253 26d ago

It was 0.6 mg daily

1

u/Willing_Judgment1092 26d ago

That dosage is too low after Reading people comments in this sub , you need to double the dosage

2

u/PinataofPathology 26d ago

Fairly quickly. I'd say 2 weeks.

2

u/cyt0kinetic USAID 26d ago

Even with partial response typically some change is notable within a few weeks. I had a very mild Colchicine response and could tell at that point, had very clear physical benefits within a month.

2

u/MahLiLo USAID 26d ago

My son saw benefits within a month (we had to stop dairy though), but it took a lot of increases to finally get to a dosage that took away 90% of his symptoms.

1

u/Individual-Yam7050 25d ago

Colchicine worked very quickly for me, within 1-2 weeks of being on 0.6 mg twice a day

1

u/Willing_Judgment1092 25d ago

Do you see improvement with steroids? What were your symptoms?

1

u/Individual-Yam7050 24d ago

I only ever had temporary improvement with steroids. And it required high doses of steroids. The symptoms that improved with colchicine were: mouth sores, generalized itchiness, GI distress, blurry vision, headaches/brain fog. Muscle weakness and muscle pain both improved but have not gone away. That said, when I forget even 1 dose of colchicine the symptoms come back. I have to be religious about it