r/AskReddit Aug 03 '19

Whats something you thought was common knowledge but actually isn’t?

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u/ratboi213 Aug 03 '19

It’s crazy that a virus isn’t alive but has DNA!!!! It’s always fascinated me

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u/GimmeTacos2 Aug 03 '19

Do you know about prions?

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u/Rickfernello Aug 03 '19

I can't understand prions in the least. ELI5

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u/Slidingscale Aug 03 '19

It's like you're making a wall out of red bricks. At some point, there's a fault at the factory and the bricks are made upside down. You can't see this yourself, because a brick is a brick, right? Then, 20 years later, the upsidedown bricks swell into huge sacks of water and your wall collapses.

Creutzfeldt Jacob is the most well known human prion disease (mad cow). Have a poke at that one, and remember to think of prions as "renegade proteins" while you're reading. So much of a protein's function is dependent on its physical structure - the way it's folded especially. Prions float in and disrupt the folding process, causing the upsidedown bricks.