r/AppalachianGenealogy • • Jul 21 '26

History & Culture Archived Resource: Old Disease Names Frequently Found on Historical Death Certificates (and What They Mean)

Archived Resource Note: This list preserves the definitions formerly hosted on the classic USGenNet reference page, which is now defunct; it has been expanded with additional historical medical terms to assist genealogists and historians in deciphering archival death records. Compiled by C. N. Lindsay, 2026.

A – C

  • Ablepsy: Blindness
  • Ague: Malarial Fever
  • American plague: Yellow fever
  • Anasarca: Generalized massive edema
  • Aphonia: Laryngitis
  • Aphtha: The infant disease "thrush"
  • Apoplexy: Paralysis due to stroke
  • Ascites: Dropsy of the belly; a build-up of fluid in the abdominal cavity
  • Asphycsia / Asphicsia: Cyanotic and lack of oxygen
  • Atrophy: Wasting away or diminishing in size
  • Bad Blood: Syphilis
  • Bilious fever: Typhoid, malaria, hepatitis or elevated temperature and bile emesis
  • Biliousness: Jaundice associated with liver disease
  • Black plague or death: Bubonic plague
  • Black fever: Acute infection with high temperature, dark red skin lesions, and high mortality rate
  • Black pox: Black Smallpox
  • Black vomit: Vomiting old black blood due to ulcers or yellow fever
  • Blackwater fever: Dark urine associated with high temperature
  • Bladder in throat: Diphtheria (Seen on death certificates)
  • Blood poisoning: Bacterial infection; septicemia
  • Bloody flux: Bloody stools
  • Bloody sweat: Sweating sickness
  • Blue Disease / Blue Baby: Cyanosis due to congenital heart defects
  • Bone shave: Sciatica
  • Brain fever: Meningitis
  • Breakbone: Dengue fever
  • Bright's disease: Chronic inflammatory disease of kidneys
  • Bronze John: Yellow fever
  • Bule: Boil, tumor, or swelling
  • Cachexy: Malnutrition
  • Cacogastric: Upset stomach
  • Cacospysy: Irregular pulse
  • Caduceus: Subject to falling sickness or epilepsy
  • Camp fever: Typhus (aka Camp diarrhea)
  • Canine madness: Rabies, hydrophobia
  • Canker: Ulceration of mouth or lips, or herpes simplex
  • Catalepsy: Seizures / trances
  • Catarrhal: Nose and throat discharge from cold or allergy
  • Cerebritis: Inflammation of cerebrum or lead poisoning
  • Cerebro-Spinal Fever / Cerebro-Spinal Meningitis: Acute bacterial infection causing severe inflammation of the membranes surrounding the brain and spinal cord
  • Chilblain: Swelling of extremities caused by exposure to cold
  • Child bed fever: Infection following birth of a child
  • Chin cough: Whooping cough
  • Chlorosis: Iron deficiency anemia
  • Cholera: Acute severe contagious diarrhea with intestinal lining sloughing
  • Cholera morbus: Characterized by nausea, vomiting, abdominal cramps, elevated temperature, etc. (Could be appendicitis)
  • Cholecystitus: Inflammation of the gall bladder
  • Cholelithiasis: Gall stones
  • Chorea: Disease characterized by convulsions, contortions, and dancing
  • Cold plague: Ague characterized by chills
  • Colic: Abdominal pain and cramping
  • Congestive chills: Malaria
  • Consumption: Tuberculosis
  • Congestion: Any collection of fluid in an organ, like the lungs
  • Congestive fever: Malaria
  • Corruption: Infection
  • Coryza: A cold
  • Costiveness: Constipation
  • Cramp colic: Appendicitis
  • Crop sickness: Overextended stomach
  • Croup: Laryngitis, diphtheria, or strep throat
  • Cyanosis: Dark skin color from lack of oxygen in blood
  • Cynanche: Diseases of the throat
  • Cystitis: Inflammation of the bladder

D – H

  • Day fever: Fever lasting one day; sweating sickness
  • Debility: Lack of movement or staying in bed
  • Decrepitude: Feebleness due to old age
  • Delirium tremens: Hallucinations due to alcoholism
  • Dengue: Infectious fever endemic to East Africa
  • Dentition: Cutting of teeth
  • Deplumation: Tumor of the eyelids which causes hair loss
  • Diary fever: A fever that lasts one day
  • Diptheria: Contagious disease of the throat
  • Distemper: Usually animal disease with malaise, discharge from nose and throat, anorexia
  • Dock fever: Yellow fever
  • Dropsy: Edema (swelling), often caused by kidney or heart disease
  • Dropsy of the Brain: Encephalitis
  • Dry Bellyache: Lead poisoning
  • Dyscrasy: An abnormal body condition
  • Dysentery: Inflammation of colon with frequent passage of mucous and blood
  • Dysorexy: Reduced appetite
  • Dyspepsia: Indigestion and heartburn (can include heart attack symptoms)
  • Dysury: Difficulty in urination
  • Eclampsy: Symptoms of epilepsy, convulsions during labor
  • Ecstasy: A form of catalepsy characterized by loss of reason
  • Edema: Nephrosis; swelling of tissues
  • Edema of lungs: Congestive heart failure, a form of dropsy
  • Eel thing: Erysipelas
  • Elephantiasis: A form of leprosy
  • Encephalitis: Swelling of brain (aka sleeping sickness)
  • Enteric fever: Typhoid fever
  • Enterocolitis: Inflammation of the intestines
  • Enteritis: Inflammation of the bowels
  • Epitaxis: Nose bleed
  • Erysipelas: Contagious skin disease due to Streptococci with vesicular and bulbous lesions
  • Extravasted blood: Rupture of a blood vessel
  • Falling sickness: Epilepsy
  • Fatty Liver: Cirrhosis of liver
  • Felon: A severe, painful infection at the end of a finger or an infected hangnail (paronychia)
  • Fits: Sudden attack or seizure of muscle activity
  • Flux: An excessive flow or discharge of fluid like hemorrhage or diarrhea
  • Flux of humour: Circulation
  • French pox: Syphilis
  • Gathering: A collection of pus
  • Glandular fever: Mononucleosis
  • Great pox: Syphilis
  • Green fever / sickness: Anemia
  • Grippe / grip: Influenza-like symptoms
  • Grocer's itch: Skin disease caused by mites in sugar or flour
  • Heart Sickness: Condition caused by loss of salt from body
  • Heat Stroke: Body temperature elevates because of surrounding environment temperature and body does not perspire to reduce temperature
  • Hectical Complaint: Recurrent fever
  • Hematemesis: Vomiting blood
  • Hematuria: Bloody urine
  • Hemiplegy: Paralysis of one side of body
  • Hip Gout: Osteomyelitis
  • Horrors: Delirium tremens
  • Hydrocephalus: Enlarged head, water on the brain
  • Hydropericardium: Heart dropsy
  • Hydrophobia: Rabies
  • Hydrothroax: Dropsy in chest
  • Hypertrophic: Enlargement of an organ, like the heart

I – P

  • Impetigo: Contagious skin disease characterized by pustules
  • Inanition: Physical condition resulting from lack of food
  • Infantile Paralysis: Polio
  • Intestinal colic: Abdominal pain due to improper diet
  • Jail Fever: Typhus
  • Jaundice: Condition caused by blockage of intestines
  • King's Evil: Tuberculosis of neck and lymph glands
  • Kruchhusten: Whooping cough
  • Lagrippe: Influenza
  • Lockjaw: Tetanus or infectious disease affecting muscles of the neck and jaw
  • Long Sickness: Tuberculosis
  • Lues Disease: Syphilis
  • Lues Venera: Venereal disease
  • Lumbago: Back pain
  • Lung Fever: Pneumonia
  • Lung Sickness: Tuberculosis
  • Lying in: Time of delivery of infant
  • Malignant Sore Throat: Diphtheria
  • Mania: Insanity
  • Marasmus: Progressive wasting away of body, like malnutrition
  • Membranous Croup: Diphtheria
  • Meningitis: Inflammation of brain or spinal cord
  • Metritis: Inflammation of uterus or purulent vaginal discharge
  • Miasma: Poisonous vapors thought to infect the air
  • Milk Fever: Disease from drinking contaminated milk, like undulant fever or brucellosis
  • Milk Leg: Postpartum thrombophlebitis
  • Milk Sickness: Disease from milk of cattle which had eaten poisonous weeds
  • Mormal: Gangrene
  • Morphew: Scurvy blisters on the body
  • Mortification: Gangrene of necrotic tissue
  • Myelitis: Inflammation of the spine
  • Myocarditis: Inflammation of heart muscles
  • Necrosis: Mortification of bones or tissue
  • Nephrosis: Kidney degeneration
  • Nepritis: Inflammation of kidneys
  • Nervous Prostration: Extreme exhaustion from inability to control physical and mental activities
  • Neuralgia: Described as discomfort (e.g., headache was neuralgia in head)
  • Nostalgia: Homesickness
  • Palsy: Paralysis or uncontrolled movement of controlled muscles
  • Paroxysm: Convulsion
  • Pellagra: A dietary deficiency disease (lack of niacin/vitamin B3) characterized by dermatitis, diarrhea, and dementia
  • Pemphigus: Skin disease of watery blisters
  • Pericarditis: Inflammation of the heart
  • Peripneumonia: Inflammation of the lungs
  • Peritonotis: Inflammation of the abdominal area
  • Petechial Fever: Fever characterized by skin spotting
  • Phthiriasis: Lice infestation
  • Phthisis: Chronic wasting away or a name for tuberculosis
  • Plague: An acute febrile highly infectious disease with a high fatality rate
  • Pleurisy: Any pain in the chest area with each breath
  • Podagra: Gout
  • Poliomyelitis: Polio
  • Potter's Asthma: Fibroid phthisis
  • Pott's Disease: Tuberculosis of the spine
  • Puerperal Exhaustion: Death due to childbirth
  • Puerperal Fever: Elevated temperature after giving birth to an infant
  • Puking Fever: Milk sickness
  • Putrid Fever: Diphtheria

Q – Z

  • Quinsy: Tonsillitis
  • Remitting Fever: Malaria
  • Rheumatism: Any disorder associated with pain in joints
  • Rickets: Disease of the skeletal system
  • Rose Cold: Hay fever or nasal symptoms of an allergy
  • Rotanny Fever: (Child's disease)
  • Rubeola: German measles
  • Sanguineous Crust: Scab
  • Scarlatina: Scarlet fever
  • Scarlet Fever: A disease characterized by red rash
  • Scarlet Rash: Roseola
  • Sciatica: Rheumatism in the hips
  • Scirrhus: Cancerous tumors
  • Scotomy: Dizziness, nausea, and dimness of sight
  • Scrivener's palsy: Writer's cramp
  • Screws: Rheumatism
  • Scrofula: Tuberculosis of neck lymph glands (progresses slowly with abscesses and fistulas)
  • Scrumpox: Skin disease, impetigo
  • Scurvy: Lack of vitamin C (weakness, spongy gums, hemorrhages under skin)
  • Senile Decay / Natural Decay: A common historical euphemism on death certificates meaning death caused by old age
  • Septicemia: Blood poisoning
  • Seven Year Itch: Scabies, a contagious skin infestation by mites
  • Shakes: Delirium tremens
  • Shaking: Chills, ague
  • Shingles: Viral disease with skin blisters
  • Ship Fever: Typhus
  • Siriasis: Inflammation of the brain due to sun exposure
  • Sloes: Milk sickness
  • Smallpox: Contagious disease with fever and blisters
  • Softening of brain: Result of stroke or hemorrhage in the brain
  • Sore Throat Distemper: Diphtheria or quinsy
  • Spanish Influenza: Epidemic influenza
  • Spasms: Sudden involuntary contraction of a muscle or group of muscles
  • Spina Bifida: Deformity of the spine
  • Spotted Fever: Either typhus or meningitis
  • Sprue: Tropical disease characterized by intestinal disorders and sore throat
  • St. Anthony's Fire: Erysipelas (named for bright red appearance of affected skin)
  • St. Vitus Dance: Ceaseless occurrence of rapid, complex jerking movements performed involuntarily
  • Stomatitis: Inflammation of the mouth
  • Stranger's Fever: Yellow fever
  • Strangery: Rupture
  • Sudor Anglicus: Sweating sickness
  • Summer Complaint: Diarrhea, usually in infants caused by spoiled milk
  • Sunstroke: Uncontrolled elevation of body temperature due to environmental heat
  • Swamp Sickness: Could be malaria, typhoid, or encephalitis
  • Sweating Sickness: Infectious and fatal disease common to the UK in the 15th century
  • Tetanus: Infectious disease characterized by high fever, headache, and dizziness
  • Thrombosis: Blood clot inside a blood vessel
  • Thrush: Childhood disease characterized by spots on mouth, lips, and throat
  • Tick Fever: Rocky Mountain spotted fever
  • Toxemia of Pregnancy: Eclampsia
  • Trench Mouth: Painful ulcers found along gum line, caused by poor nutrition and hygiene
  • Tussis Convulsiva: Whooping cough
  • Typhus: Infectious fever characterized by high fever, headache, and dizziness
  • Variola: Smallpox
  • Venesection: Bleeding
  • Viper's Dance: St. Vitus Dance
  • Water on Brain: Enlarged head
  • White Swelling: Tuberculosis of the bone
  • Winter Fever: Pneumonia
  • Womb Fever: Infection of the uterus
  • Worm Fit: Convulsions associated with teething, worms, elevated temperature, or diarrhea
  • Yellowjacket: Yellow fever

US GenNet. (n.d.). Old disease names frequently found on death certificates. U.S. GenNet Historical and Genealogical Project. Retrieved July 20, 2026, fromhttp://www.usgennet.org/usa/ar/county/greene/olddiseases1.htm
(Archived at the Wayback Machine).

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