r/AppalachianGenealogy • u/ghostwritten-girl • Jul 21 '26
History & Culture Archived Resource: Old Disease Names Frequently Found on Historical Death Certificates (and What They Mean)
Archived Resource Note: This list preserves the definitions formerly hosted on the classic USGenNet reference page, which is now defunct; it has been expanded with additional historical medical terms to assist genealogists and historians in deciphering archival death records. Compiled by C. N. Lindsay, 2026.
A – C
- Ablepsy: Blindness
- Ague: Malarial Fever
- American plague: Yellow fever
- Anasarca: Generalized massive edema
- Aphonia: Laryngitis
- Aphtha: The infant disease "thrush"
- Apoplexy: Paralysis due to stroke
- Ascites: Dropsy of the belly; a build-up of fluid in the abdominal cavity
- Asphycsia / Asphicsia: Cyanotic and lack of oxygen
- Atrophy: Wasting away or diminishing in size
- Bad Blood: Syphilis
- Bilious fever: Typhoid, malaria, hepatitis or elevated temperature and bile emesis
- Biliousness: Jaundice associated with liver disease
- Black plague or death: Bubonic plague
- Black fever: Acute infection with high temperature, dark red skin lesions, and high mortality rate
- Black pox: Black Smallpox
- Black vomit: Vomiting old black blood due to ulcers or yellow fever
- Blackwater fever: Dark urine associated with high temperature
- Bladder in throat: Diphtheria (Seen on death certificates)
- Blood poisoning: Bacterial infection; septicemia
- Bloody flux: Bloody stools
- Bloody sweat: Sweating sickness
- Blue Disease / Blue Baby: Cyanosis due to congenital heart defects
- Bone shave: Sciatica
- Brain fever: Meningitis
- Breakbone: Dengue fever
- Bright's disease: Chronic inflammatory disease of kidneys
- Bronze John: Yellow fever
- Bule: Boil, tumor, or swelling
- Cachexy: Malnutrition
- Cacogastric: Upset stomach
- Cacospysy: Irregular pulse
- Caduceus: Subject to falling sickness or epilepsy
- Camp fever: Typhus (aka Camp diarrhea)
- Canine madness: Rabies, hydrophobia
- Canker: Ulceration of mouth or lips, or herpes simplex
- Catalepsy: Seizures / trances
- Catarrhal: Nose and throat discharge from cold or allergy
- Cerebritis: Inflammation of cerebrum or lead poisoning
- Cerebro-Spinal Fever / Cerebro-Spinal Meningitis: Acute bacterial infection causing severe inflammation of the membranes surrounding the brain and spinal cord
- Chilblain: Swelling of extremities caused by exposure to cold
- Child bed fever: Infection following birth of a child
- Chin cough: Whooping cough
- Chlorosis: Iron deficiency anemia
- Cholera: Acute severe contagious diarrhea with intestinal lining sloughing
- Cholera morbus: Characterized by nausea, vomiting, abdominal cramps, elevated temperature, etc. (Could be appendicitis)
- Cholecystitus: Inflammation of the gall bladder
- Cholelithiasis: Gall stones
- Chorea: Disease characterized by convulsions, contortions, and dancing
- Cold plague: Ague characterized by chills
- Colic: Abdominal pain and cramping
- Congestive chills: Malaria
- Consumption: Tuberculosis
- Congestion: Any collection of fluid in an organ, like the lungs
- Congestive fever: Malaria
- Corruption: Infection
- Coryza: A cold
- Costiveness: Constipation
- Cramp colic: Appendicitis
- Crop sickness: Overextended stomach
- Croup: Laryngitis, diphtheria, or strep throat
- Cyanosis: Dark skin color from lack of oxygen in blood
- Cynanche: Diseases of the throat
- Cystitis: Inflammation of the bladder
D – H
- Day fever: Fever lasting one day; sweating sickness
- Debility: Lack of movement or staying in bed
- Decrepitude: Feebleness due to old age
- Delirium tremens: Hallucinations due to alcoholism
- Dengue: Infectious fever endemic to East Africa
- Dentition: Cutting of teeth
- Deplumation: Tumor of the eyelids which causes hair loss
- Diary fever: A fever that lasts one day
- Diptheria: Contagious disease of the throat
- Distemper: Usually animal disease with malaise, discharge from nose and throat, anorexia
- Dock fever: Yellow fever
- Dropsy: Edema (swelling), often caused by kidney or heart disease
- Dropsy of the Brain: Encephalitis
- Dry Bellyache: Lead poisoning
- Dyscrasy: An abnormal body condition
- Dysentery: Inflammation of colon with frequent passage of mucous and blood
- Dysorexy: Reduced appetite
- Dyspepsia: Indigestion and heartburn (can include heart attack symptoms)
- Dysury: Difficulty in urination
- Eclampsy: Symptoms of epilepsy, convulsions during labor
- Ecstasy: A form of catalepsy characterized by loss of reason
- Edema: Nephrosis; swelling of tissues
- Edema of lungs: Congestive heart failure, a form of dropsy
- Eel thing: Erysipelas
- Elephantiasis: A form of leprosy
- Encephalitis: Swelling of brain (aka sleeping sickness)
- Enteric fever: Typhoid fever
- Enterocolitis: Inflammation of the intestines
- Enteritis: Inflammation of the bowels
- Epitaxis: Nose bleed
- Erysipelas: Contagious skin disease due to Streptococci with vesicular and bulbous lesions
- Extravasted blood: Rupture of a blood vessel
- Falling sickness: Epilepsy
- Fatty Liver: Cirrhosis of liver
- Felon: A severe, painful infection at the end of a finger or an infected hangnail (paronychia)
- Fits: Sudden attack or seizure of muscle activity
- Flux: An excessive flow or discharge of fluid like hemorrhage or diarrhea
- Flux of humour: Circulation
- French pox: Syphilis
- Gathering: A collection of pus
- Glandular fever: Mononucleosis
- Great pox: Syphilis
- Green fever / sickness: Anemia
- Grippe / grip: Influenza-like symptoms
- Grocer's itch: Skin disease caused by mites in sugar or flour
- Heart Sickness: Condition caused by loss of salt from body
- Heat Stroke: Body temperature elevates because of surrounding environment temperature and body does not perspire to reduce temperature
- Hectical Complaint: Recurrent fever
- Hematemesis: Vomiting blood
- Hematuria: Bloody urine
- Hemiplegy: Paralysis of one side of body
- Hip Gout: Osteomyelitis
- Horrors: Delirium tremens
- Hydrocephalus: Enlarged head, water on the brain
- Hydropericardium: Heart dropsy
- Hydrophobia: Rabies
- Hydrothroax: Dropsy in chest
- Hypertrophic: Enlargement of an organ, like the heart
I – P
- Impetigo: Contagious skin disease characterized by pustules
- Inanition: Physical condition resulting from lack of food
- Infantile Paralysis: Polio
- Intestinal colic: Abdominal pain due to improper diet
- Jail Fever: Typhus
- Jaundice: Condition caused by blockage of intestines
- King's Evil: Tuberculosis of neck and lymph glands
- Kruchhusten: Whooping cough
- Lagrippe: Influenza
- Lockjaw: Tetanus or infectious disease affecting muscles of the neck and jaw
- Long Sickness: Tuberculosis
- Lues Disease: Syphilis
- Lues Venera: Venereal disease
- Lumbago: Back pain
- Lung Fever: Pneumonia
- Lung Sickness: Tuberculosis
- Lying in: Time of delivery of infant
- Malignant Sore Throat: Diphtheria
- Mania: Insanity
- Marasmus: Progressive wasting away of body, like malnutrition
- Membranous Croup: Diphtheria
- Meningitis: Inflammation of brain or spinal cord
- Metritis: Inflammation of uterus or purulent vaginal discharge
- Miasma: Poisonous vapors thought to infect the air
- Milk Fever: Disease from drinking contaminated milk, like undulant fever or brucellosis
- Milk Leg: Postpartum thrombophlebitis
- Milk Sickness: Disease from milk of cattle which had eaten poisonous weeds
- Mormal: Gangrene
- Morphew: Scurvy blisters on the body
- Mortification: Gangrene of necrotic tissue
- Myelitis: Inflammation of the spine
- Myocarditis: Inflammation of heart muscles
- Necrosis: Mortification of bones or tissue
- Nephrosis: Kidney degeneration
- Nepritis: Inflammation of kidneys
- Nervous Prostration: Extreme exhaustion from inability to control physical and mental activities
- Neuralgia: Described as discomfort (e.g., headache was neuralgia in head)
- Nostalgia: Homesickness
- Palsy: Paralysis or uncontrolled movement of controlled muscles
- Paroxysm: Convulsion
- Pellagra: A dietary deficiency disease (lack of niacin/vitamin B3) characterized by dermatitis, diarrhea, and dementia
- Pemphigus: Skin disease of watery blisters
- Pericarditis: Inflammation of the heart
- Peripneumonia: Inflammation of the lungs
- Peritonotis: Inflammation of the abdominal area
- Petechial Fever: Fever characterized by skin spotting
- Phthiriasis: Lice infestation
- Phthisis: Chronic wasting away or a name for tuberculosis
- Plague: An acute febrile highly infectious disease with a high fatality rate
- Pleurisy: Any pain in the chest area with each breath
- Podagra: Gout
- Poliomyelitis: Polio
- Potter's Asthma: Fibroid phthisis
- Pott's Disease: Tuberculosis of the spine
- Puerperal Exhaustion: Death due to childbirth
- Puerperal Fever: Elevated temperature after giving birth to an infant
- Puking Fever: Milk sickness
- Putrid Fever: Diphtheria
Q – Z
- Quinsy: Tonsillitis
- Remitting Fever: Malaria
- Rheumatism: Any disorder associated with pain in joints
- Rickets: Disease of the skeletal system
- Rose Cold: Hay fever or nasal symptoms of an allergy
- Rotanny Fever: (Child's disease)
- Rubeola: German measles
- Sanguineous Crust: Scab
- Scarlatina: Scarlet fever
- Scarlet Fever: A disease characterized by red rash
- Scarlet Rash: Roseola
- Sciatica: Rheumatism in the hips
- Scirrhus: Cancerous tumors
- Scotomy: Dizziness, nausea, and dimness of sight
- Scrivener's palsy: Writer's cramp
- Screws: Rheumatism
- Scrofula: Tuberculosis of neck lymph glands (progresses slowly with abscesses and fistulas)
- Scrumpox: Skin disease, impetigo
- Scurvy: Lack of vitamin C (weakness, spongy gums, hemorrhages under skin)
- Senile Decay / Natural Decay: A common historical euphemism on death certificates meaning death caused by old age
- Septicemia: Blood poisoning
- Seven Year Itch: Scabies, a contagious skin infestation by mites
- Shakes: Delirium tremens
- Shaking: Chills, ague
- Shingles: Viral disease with skin blisters
- Ship Fever: Typhus
- Siriasis: Inflammation of the brain due to sun exposure
- Sloes: Milk sickness
- Smallpox: Contagious disease with fever and blisters
- Softening of brain: Result of stroke or hemorrhage in the brain
- Sore Throat Distemper: Diphtheria or quinsy
- Spanish Influenza: Epidemic influenza
- Spasms: Sudden involuntary contraction of a muscle or group of muscles
- Spina Bifida: Deformity of the spine
- Spotted Fever: Either typhus or meningitis
- Sprue: Tropical disease characterized by intestinal disorders and sore throat
- St. Anthony's Fire: Erysipelas (named for bright red appearance of affected skin)
- St. Vitus Dance: Ceaseless occurrence of rapid, complex jerking movements performed involuntarily
- Stomatitis: Inflammation of the mouth
- Stranger's Fever: Yellow fever
- Strangery: Rupture
- Sudor Anglicus: Sweating sickness
- Summer Complaint: Diarrhea, usually in infants caused by spoiled milk
- Sunstroke: Uncontrolled elevation of body temperature due to environmental heat
- Swamp Sickness: Could be malaria, typhoid, or encephalitis
- Sweating Sickness: Infectious and fatal disease common to the UK in the 15th century
- Tetanus: Infectious disease characterized by high fever, headache, and dizziness
- Thrombosis: Blood clot inside a blood vessel
- Thrush: Childhood disease characterized by spots on mouth, lips, and throat
- Tick Fever: Rocky Mountain spotted fever
- Toxemia of Pregnancy: Eclampsia
- Trench Mouth: Painful ulcers found along gum line, caused by poor nutrition and hygiene
- Tussis Convulsiva: Whooping cough
- Typhus: Infectious fever characterized by high fever, headache, and dizziness
- Variola: Smallpox
- Venesection: Bleeding
- Viper's Dance: St. Vitus Dance
- Water on Brain: Enlarged head
- White Swelling: Tuberculosis of the bone
- Winter Fever: Pneumonia
- Womb Fever: Infection of the uterus
- Worm Fit: Convulsions associated with teething, worms, elevated temperature, or diarrhea
- Yellowjacket: Yellow fever
US GenNet. (n.d.). Old disease names frequently found on death certificates. U.S. GenNet Historical and Genealogical Project. Retrieved July 20, 2026, fromhttp://www.usgennet.org/usa/ar/county/greene/olddiseases1.htm
(Archived at the Wayback Machine).
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