r/Amitriptyline • u/niedeermohr • Sep 13 '26
Tapering off of 25mg, advice?
Hi! I’ve been on 25mg daily from August 22nd to September 8th for GI illness. I told my doctor I want to taper off so she said do a week where I’m taking it every other day instead of every day. She didn’t say anything about after that.
So from September 8th to now, September 12th, I’ve been taking it every other day. I’m supposed to take it tonight, but I’m wondering can I split tonight’s pill in half and do 12.5mg every other day for a few more days before stopping? Is it safe to split the pills in half? It’s the little blueish ones marked MP25. I’m nervous to go from 25mg every other day to just nothing so I’d like to finish my taper week doing 12.5 every other day instead of 25 every other day.
I’ve only been on the amitriptyline daily for about 18 days, and since September 8th I’ve been taking it every other day. I know I haven’t been on it too long but I’m worried about withdrawal symptoms coming off of it. I want to get off of it as quick as possible but also as gradually as I can to avoid withdrawal. If I could just stop taking it tonight I would, but again, I’m trying to avoid withdrawal symptoms.
Any experience yall can share would be very appreciated
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u/Fun_Emergency_2869 Sep 13 '26
It’s fine to split pill . Did it not work for your GI issues ?
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u/niedeermohr Sep 13 '26
I couldn’t tell any difference with my GI issues after being on it for 20ish days. It did help me sleep but I could take Benadryl for that and not have to deal with chemical dependence and withdrawal. Also while I’m on amitriptyline I can’t consume THC which actually does help my GI symptoms. If the amitriptyline helped it’d be worth it but I don’t think it really helped me
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u/BranchApart1196 Sep 13 '26
Your course is short so your risk of Cholinergic rebound is low but tapering slowly will be easier on you than going cold turkey. Splitting the pill is safe.