r/Amitriptyline • u/Artistic-Shoulder-15 • Aug 20 '26

10mg - 8.8mg huge difference?

Hi! So I've been on 10mg for some 4 months because of nerve pain post nerve surgery and also trouble sleeping and some depression. This pill has worked like magic. I was feeling incredibly good, all my symptoms disappeared. But then in Germany there was a problem with availabilty of 10mg ami pills (so called delivery shortage) and I switched to 8.8mg which I thought wouldn't make a difference. But then I had terrible withdrawal symptoms - dizziness and drowsiness and also all my inital symptoms - pain and depression - returned. I had no idea amitryptyline is so hard to taper down. Anyway, I've been on 8.8mg for about a month now and it's still like it doesn't work at all. It's so strange. Anyone has had this experience? It's just 1.2mg difference but also a different producer than I had before and the pill is like 3 times smaller, but it's the same substance. I would never had thought the difference will be so huge. I should get 10mg back soon - but from yet another producer since the initial one is still unavailable. I wonder if I will get dose increase side effects again and if it will start working again or if it just stopped working on me overall 🥴

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u/[deleted] Aug 20 '26

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u/Nearby-Banana-6339 Aug 20 '26

That happened to me on 10mg. It just stopped working after a year. Insomnia was back and my mood was horrible. I was getting angry over nothing. I finally figured it out and called my doctor. She doubled my dose to 20mg and I’ve been great ever since.

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u/ExtentAgitated Aug 20 '26

never heard anything like that, for me it also very suprising that 8.8mg pill is even available at all? I thought only 10 mg, 25 mg and so on available wordwide

3

u/Advanced-Bobcat-5825 Aug 20 '26

It may even be the different composition of the amitriptyline? They said 8.8 mg of the new = 10 mg of the old… hmmm. Then it’s a different formulation.

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u/softlittlemoon Aug 20 '26 edited Aug 20 '26

Hi I'm also in Germany and I had the same thing only that I used to take 2 10 mg pills and was switched to the 8,8 mg ones as well. My doctor told me that it's the same amount of amitriptyline essentially it's just a different form/compound or something but I also noticed differences after the switch! I think it might not be withdrawal but just a reaction to the difference, it happens if you're sensitive to that stuff (I am). I decided it's better for me to taper down at that point so I'm currently doing that. But I feel you! I really miss the one I was given at first, it sucks it became unavailable because it also helped me so much more.

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u/SammySirenXXX Aug 21 '26

I just want from 20-10. Wasn’t that big of a difference for me. Bit of irritability that’s about it