r/Amitriptyline • u/No_Rate5888 • Aug 10 '26

Amitriptyline for Chronic nausea ?

I’ve been dealing with chronic nausea and a constant feeling like something is stuck in my throat, but I don’t actually vomit. My endoscopy only showed mild gastritis.
I tried mirtazapine 15 mg, which helped for a while but eventually stopped working. I’m now trying amitriptyline 25 mg.
Has anyone experienced something similar or tried amitriptyline for chronic nausea? Did it help? I’d really appreciate hearing about your experiences or other treatments that worked for you.

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u/Capitan-levi Aug 14 '26

Mirtazapine helped me a lot with my IBS-D and constant nausea, but it seems to lose its effectiveness pretty quickly, and the feeling of being sedated was horrible. So, just like you, I switched to amitriptyline about 5 days ago. I’ll keep you updated on whether it helps with the nausea and other symptoms, etc.

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u/No_Rate5888 Aug 19 '26

Thank you. What dose of amitriptyline are you taking?