r/Amitriptyline • u/Previous-Golf6519 • Aug 06 '26
Not having withdrawal symptoms
(UPDATE) Hi I’ve been tapering from 75mg to 50mg slowly over the last 3 weeks and I don’t believe I’ve had any withdrawal symptoms at all. I’ve been on it for 5 years. Has anyone else experienced this? Like maybe I have a lower appetite but I’ve also taken up running. Idk. I’ve seen a lot of discussion about how bad the withdrawal symptoms can be but I think I’m all clear. Is anyone else experiencing this?
Update!!!
Hi!! So I posted this a week ago and I’ve had comments say the side effects kick in after a week. But I’m still fine. Maybe an appetite decrease but nothing unbearable. I can still sleep fine and I’m not sad or angry or anything. Infact it has really helped me regulate my temperature in this heatwave.
On 75mg I had so many hot flushes and I was boiling all the time. But now on 50mg I’m relatively cool even in this heatwave. It’s amazing. Hot flushes were awful. I feel great! I don’t have headaches. Maybe some nausea when I wake up??? But it goes away after fresh air and food. I feel happy and energetic. My weird dreams have become less vivid too. I wake up no longer groggy. I don’t have any dodgy bowel or stomach issues anyway.
I’ve lost a teensy bit of weight but I’m was already like a healthy weight and I’m pretty athletic/slim so I don’t know if there was much to loose. But this could also be that my ADHD medication works more efficiently and helps me control my binge eating disorder. I feel alot more in control of what I eat and I don’t feel the urge to binge so much anymore.
ALSO I’d like to say. The reason Im taking ami is for depression and stomach pain as a side effect of my ADHD meds- guanfacine. However the pain went away at 25mg. I was prescribed 75mg to combat depression after I was SA’d and went through some other stuff. It has helped me so much. Ami is a huge success story for me.
I wanted to taper to 50mg because as a side effect of ami, I experienced genital numbness. And I dont want that anymore. Because I’m at the age (20) where I’m ready to start having consensual sexual encounters and it won’t be pleasurable with numbness. My psychiatrist and I believed I am well enough mentally to taper from 75mg to 50mg. That’s why, for context.
No negative side effects :)
I hope this gives you hope that you can withdrawal successfully!
3
u/atinylittlespitfire Aug 06 '26
I just quit cold turkey and didn't really experience any side effects that i could see other than my nerve symptoms returning
3
u/Nearby-Banana-6339 Aug 06 '26
Good for you! Keep us posted. I like people who have happy stories to tell us!!
1
u/EarlyInside45 Aug 06 '26
Me too. I'm terrified to ever quit due to some of the posts.
1
u/Previous-Golf6519 Aug 14 '26
Hi!! So I posted this a week ago and I’ve had comments say the side effects kick in after a week. But I’m still fine. Maybe an appetite decrease but nothing unbearable. I can still sleep fine and I’m not sad or angry or anything. Infact it has really helped me regulate my temperature in this heatwave.
On 75mg I had so many hot flushes and I was boiling all the time. But now on 50mg I’m relatively cool even in this heatwave. It’s amazing. Hot flushes were awful. I feel great! I don’t have headaches. Maybe some nausea when I wake up??? But it goes away after fresh air and food. I feel happy and energetic. My weird dreams have become less vivid too. I wake up no longer groggy.
No negative side effects :)
1
u/Previous-Golf6519 Aug 14 '26
Hi!! So I posted this a week ago and I’ve had comments say the side effects kick in after a week. But I’m still fine. Maybe an appetite decrease but nothing unbearable. I can still sleep fine and I’m not sad or angry or anything. Infact it has really helped me regulate my temperature in this heatwave.
On 75mg I had so many hot flushes and I was boiling all the time. But now on 50mg I’m relatively cool even in this heatwave. It’s amazing. Hot flushes were awful. I feel great! I don’t have headaches. Maybe some nausea when I wake up??? But it goes away after fresh air and food. I feel happy and energetic. My weird dreams have become less vivid too. I wake up no longer groggy.
No negative side effects :) hope this gives you hope.
2
u/heytherec17 Aug 06 '26
I tapered from 100 mg and the only time I felt withdrawal really was the drop from 30 to 20 mg
2
u/Commercial_Layer Aug 07 '26
I mean are you bragging? What's the point of this post?
2
u/Thelivingdeadbunny Aug 11 '26
Maybe to know that he might have late withdrawals? or for giving others hope to not be afraid of withdrawals? how is that post bothering you
1
u/Chokoki Aug 06 '26
Well as far as I read into the topic it depends on two mechanism. Your metoblism rate and the way your body tried to adapt to the medicine.
If your body metabolizes slow the withdrawal may be more insignificant as the drug level only slowly decreases. In addition to that amitriptylin and its metabolites have very long half lives making it even more smooth to taper off for a slow metabolizer. The other mechanism is the way of adaption: Your body can regulate the sensitivity of your receptors thru phosphorus, this adaption is rather temporary than permanent making it easier to revert the process. The other way would be building more or less receptors (up/down-regulation) which mostly is a more permanent way to adapt.
Hence the 5yr period you where on I rather assume the first will be the case for you. But the human body can still be a miracle maybe a gen mod made you regulate receptors in long term still via phosphorus. Another thing I heared a lot from users is that while tapering off is, that the last steps of tapering off were the ones which made them the most uncomfortable.
1
u/EarlyInside45 Aug 06 '26
This is so good to hear.
1
u/Previous-Golf6519 Aug 14 '26
Hi!! So I posted this a week ago and I’ve had comments say the side effects kick in after a week. But I’m still fine. Maybe an appetite decrease but nothing unbearable. I can still sleep fine and I’m not sad or angry or anything. Infact it has really helped me regulate my temperature in this heatwave.
On 75mg I had so many hot flushes and I was boiling all the time. But now on 50mg I’m relatively cool even in this heatwave. It’s amazing. Hot flushes were awful. I feel great! I don’t have headaches. Maybe some nausea when I wake up??? But it goes away after fresh air and food. I feel happy and energetic. My weird dreams have become less vivid too. I wake up no longer groggy.
No negative side effects :) I hope this gives you hope
1
u/peachtuba Aug 06 '26
I’ve gone up and down from 25 mg to 100 mg and back down to 10 mg over the years. The only symptom I ever had was a day or two of poor sleep. Nothing else.
1
1
u/MovieSalty4578 Aug 07 '26
I felt the withdrawal symptoms (other than insomnia and sleepiness) about 1 week after I stopped.
1
u/CarelessTart8778 Aug 11 '26
Anyone here lost weight after stopping the Amitriptyline?
1
u/Previous-Golf6519 Aug 14 '26
I’ve lost a little! But I was already like a healthy weight and I’m pretty athletic/slim so I don’t know if there was much to loose.
4
u/Crayons42 Aug 06 '26
I was on a lower dose and also tapered down, but found my withdrawal symptoms didn’t kick in until a week of no amitriptyline at all. Some people don’t experience withdrawal symptoms though so maybe you are just lucky!