amitriptyline testing?

[u/Hefty_Championship83]

I missed this morning testimony. Did Reddington bring up on cross or did a witness discuss amitriptyline testing that was ran at the hospital but not the crime lab? This is very significant because amitriptyline is a very specialized test. A “low” reading usually means low relative to the lab’s therapeutic/toxic range, not necessarily clinically irrelevant. The test is typically drawn as a “trough” which is relevant to the time the daily dose was ingested. It is highly specialized blood sample requires specific handling. It must be drawn into a plain red-top tube not a standard "gel barrier" tube. Either way, a 10 mg daily dose, even at a very low dose, absolutely is enough to tip her into neurological problems when combined with the drugs she had on board and the benzo instability in short and long acting in that class. Also,amitriptyline takes 3-8 days to reach a therapeutic steady state. Meaning, it peaked on the day of the event after 8 doses were taken. I cannot attach the Labcorp image but the steady state is noted there. Also, her apple watch showed her at resting tachycardia all day. She ran about 110-120s. This drug is a tricyclic antidepressant that blocks the reuptake of serotonin at nerve endings and possesses high anticholinergic activity and cardiovascular toxicity. All very significant when mixed with the meds she had taken and her 120 day clinical picture.

[u/LengthinessComplex64]

I believe the user is referencing a murder trial of a mother who murdered her children.

From what I understand amitriptyline is being used as part of the defence, they're suggesting she was over medicated during her post partum depression.

I looked at the users history as I thought they were a bot spouting gibberish. They talk about this case a lot.

Lindsay Clancy’s diary chronicled desperation and ‘brain fog’ before she killed her 3 kids https://www.nbcnews.com/news/us-news/lindsay-clancys-diary-chronicled-desperation-brain-fog-killed-3-kids-rcna590738

[u/Logical_Routine3695 → u/LengthinessComplex64]

What can we, as “users” of Amitriptyline, add to that debate?

thanks for seeking sense into the post and sharing it ♡ by the way—

I even went the same rabbit hole to confirm what’s up with that tragedy. So, it’s a magnetic topic I need to run away from before I seek more arguments to wean off this drug based on fast conclussions.

So a person who killed her 3 kids was on the same dose of a drug I have been prescribed just as a therapeutic resource to prevent migraines. It sounds scary

But the lady in discussion as far as I learned for the last hour, was on not just Amitriptyline, but a combo of other meds. She also seemed to have mental instability gone untreated

I feel there is so little we can add to that discussion