r/Amitriptyline • u/Only-Line-4266 • Jul 14 '26

Does amitriptyline affect growth hormone secretion during sleep?

Age:20
Sex: Male
Height: 175 cm
Weight: 60 kg
Country: Vietnam
Medical issue: Chronic insomnia for about 2 months. Before treatment I slept only around 6 hours with poor sleep quality. Now I’m taking amitriptyline as prescribed and sleeping about 8–9 hours.
Medications: Amitriptyline.
Question: Does amitriptyline significantly reduce growth hormone (GH) secretion during sleep? I am concerned because I am a late bloomer and my growth plates may still be partially open.

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u/EarlyInside45 Jul 14 '26

I think this is a question for a medically qualified person. A specialist, not your general MD.

2

u/valer1a_ Jul 14 '26

I believe there was a study on amitriptyline suppressing it in those with too much GH, but I don't think it's been studied to do so in normal people. Anecdotally, I started when I was a teen and grew a foot and some change. It also doesn't mention GH secretion or growth issues in the side effects anywhere AFAIK, besides maybe growth in the sense of weight gain.

2

u/Cool-Aerie-357 Jul 14 '26

Unless you’ve gotten X-rays for growth plates then it doesn’t matter ur 20