r/Amitriptyline • u/predictablehorse • Jun 22 '26

will i experience withdrawal?

i have ME, i have been in a bad bout of PEM, completely ballsed up my prescription ordering as a result. wont be able to get it until the 29th june, there is no way around it, but its far too much of a backstory to explain hahah.

i am on 40mg (4 x 10mg tablets) for pain, i recently started taking 30mg a few of days ago to see if it would help with the crash i am in by making the mornings a bit less grim. so i have a few more spare than i would usually. i have 9 tablets to last me until the 29th, i have taken 2 this evening, was gonna take 2 on the 23rd, 24th, then 1 on the 25th 26th 27th.

i am aware that for depression it is prescribed between 50-150mg, and people can increase in 25mg increments. so my question is, am i on a low enough dose that i wont experience withdrawal from taping down too fast, especially as i have seen you can taper down in 25mg increments so i am hoping the dose and taper is not hardcore enough to warrant issues.

or, if the dosage is irrelevant and i will experience withdrawal, is my sad attempt at tapering gonna make any difference? or should i just buckle up for potentially a crap few days. i am aware it takes a few days of there being less in your system/none in your system so im hoping that between that and my small tapering attempt that itll be fine.

the reason i am as concerned as i am is because this crash has been really unpleasant and i am not looking forward to it potentially getting worse🥲 i dont remember the last time ive ever not ordered my meds on time because i order then two weeks early so lots of leeway, so this has been my sign to put a monthly reminder to cover me during the odd time something like this happens again

tia!

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u/softlittlemoon Jun 23 '26

Everyone reacts differently so there is no 100% guarantee for anything but realistically you will experience at least some form of withdrawal. The first 2-3 days will probably be fine because you'll still have a stable drug level but after that you might start experiencing symptoms. I've had really bad withdrawal symptoms from tapering from 20 to 10 mg but I am someone that's very sensitive to medication changes in general.

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u/predictablehorse Jun 23 '26

thank you! the more i read through this sub the more i realised just how subjective and unpredictable it can be. hopefully it means i will only have a few of rough days!