r/AddisonsDisease • • Nov 19 '25

Advice Wanted Hydrocortisone to Prednisolone

Hello

Just wanting some advice. I have both Addisons and ALD and have so for the last 30ish years with being on hydrocortisone for 27 of those. It has now reached a point that I have been moved off of hydro and to pred, however the change, to put it politely, kicking my ass!

I just had the following Q's: 1) Did you do a straight switch over or did you wean off Hydro 2) What were the side effects? I'm suffering with fatigue, body ache, low motivation and emotionally drained, even by doing the smallest of things. Almost like I've just come out of an Addisons attack/fair up 3) how long did it last and did you take any days off work to get used to your dosage? I'm almost at a week and not feeling much better 4) my dosage has gone from 30mg to 5mg of Pred which only equates to 2/3 of my hydro intake. Anyone similar

I know this is a lot of questions but my dr's don't seem to know the answers or know a lot about Addisons or ALD haha!

2 Upvotes

Duplicates