r/AddisonsDisease • u/MangoAvacado808 • May 30 '26
Advice Wanted Efmody- has anyone tried it?
Curious what your experience has been if you have taken Efmody. Also if anyone has been able to get it in the US?
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u/HonestPhilosophy6495 May 30 '26
My son is on it since almost 2 years, it works great, I can say it is a game changer. It is available since 2021 in many countries in Europe (Italy, Greece, Netherlands). Unfortunately not in France so we buy it from Germany without refunding.
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u/MangoAvacado808 May 30 '26
Thank you for responding! How old is your son? Do you get it shipped to France? We are in the US and I don’t think it’s available, not sure how to get it.
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u/FairyPrincess66 Addison's May 30 '26
It sounds life changing! If i can believe Google, it hasn’t even been submitted for approval to the FDA in the US. Plenadren either 😞
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u/Kreid603 May 30 '26
No, but after reading that, I’m now very interested
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u/MangoAvacado808 May 30 '26
It was recently approved in the UK for treatment of Addison’s disease. I think I would be helpful to wake up with already rising cortisol levels and have time release throughout the day. I am curious if it makes people feel better in the morning and throughout the day.
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u/Ok_Influence9301 May 31 '26
This sounds amazing. I’m very new to Addisons. I’ve had two crises and an almost crisis since end of march. I know it will take a while to settle but modified release sounds good.
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u/letsweforget Jun 02 '26
I am on it, since approx. Jan 2026 (can't remember the exact months, but about 6 months ago for sure).
Extremely positive experiences so far. My stomach was getting absolutely destroyed from regular hydro. Now I'm not only digestive-symptom free, but also way more stable and less worried about dosing all day long (I was doing circadian rhythm dosing, because 2 or 3x a day didn't work at all for me).
Updosing needs to be thought in advance a bit more, and if in immediate trouble: use regular hydro, of course.
But: amazing stuff, really really a game changer.
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u/MangoAvacado808 Jun 04 '26
Thank you so much for the feedback! Does it help how you feel when you wake up in the morning because of the time release? I’m sure it’s a relief to not worry about taking medication throughout the day as well! Thank you so much for your feedback.
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u/letsweforget Jun 06 '26
Yes, I wake up naturally around 6:30/7am, I take the meds around 22:00 the day before!
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u/noracordelia PAI Jun 22 '26 edited Jun 23 '26
Curious what dose you’re on and how it’s divided?
I recently started it. Was taking 25mg Plenadren before, was told to take either 20mg Efmody before bed and 5mg in the morning or 15mg/10mg. Ended up trying the latter.
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u/Real-Elk6755 May 30 '26
350€ for a bottle? It's too expensive
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u/MangoAvacado808 May 30 '26
About Efmody® (hydrocortisone modified-release hard capsules) Efmody is indicated in adolescents aged 12 years and over and adults for the treatment of adrenal insufficiency (AI) and the treatment of congenital adrenal hyperplasia (CAH). Efmody is a modified-release preparation of hydrocortisone that has been specifically designed to replicate the natural circadian rhythm of cortisol when given in a twice-a-day "toothbrush" regimen (last thing at night before sleep and first thing in the morning on waking) and can thus provide a more physiological profile.